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Molecules, Volume 30, Issue 24

December-2 2025 - 23 articles

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Articles (21)

  • Article
  • Open Access

Metallomic Aspects of Stroke and Recovery: ICP-MS Study with Chemometric Analysis

  • Bartłomiej Rospond,
  • Aleksander Matusiak,
  • Elżbieta U. Stolarczyk,
  • Joanna Piotrowska,
  • Bartosz Pomierny,
  • Weronika Krzyżanowska,
  • Przemysław W. Szafrański and
  • Przemysław Dorożyński

5 December 2025

Stroke remains a leading cause of death and disability worldwide, yet the contribution of elemental imbalance to its pathogenesis is not fully understood. Experimental evidence suggests that disturbances in the concentrations of essential and toxic e...

  • Article
  • Open Access

Lighting Up DNA in the Near-Infrared: An Os(II)–pydppn Complex with Light-Switch Behavior

  • Emanuela Trovato,
  • Salvatore Genovese,
  • Maurilio Galletta,
  • Sebastiano Campagna,
  • Maria Letizia Di Pietro and
  • Fausto Puntoriero

5 December 2025

The osmium(II) polypyridyl complex [Os(tpy)(pydppn)]2+ (tpy = 2,2′:6′,2″-terpyridine; pydppn = 3-(pyrid-2′-yl)-4,5,9,16-tetraaza-dibenzo[a,c]naphthacene) was synthesized and characterized to evaluate the effect of an extended...

  • Article
  • Open Access

Insight into the Molecular and Structural Changes in Red Pepper Induced by Direct and Indirect Ultrasonic Treatments

  • Katarzyna Rybak,
  • Aleksandra Skarżyńska,
  • Szymon Ossowski,
  • Magdalena Dadan,
  • Katarzyna Pobiega and
  • Małgorzata Nowacka

5 December 2025

This study provides a comprehensive assessment of the effect of direct (probe) and indirect (bath) ultrasound treatments on the physicochemical and structural properties of red bell pepper (Capsicum annuum L.) tissue. Ultrasound was applied under con...

  • Retraction
  • Open Access

RETRACTED: Chae et al. Anticancer Activity of 2-O-Caffeoyl Alphitolic Acid Extracted from the Lichen, Usnea barbata 2017-KL-10. Molecules 2021, 26, 3937

  • Hae-Jung Chae,
  • Geum-Jin Kim,
  • Barsha Deshar,
  • Hyun-Jin Kim,
  • Min-Ji Shin,
  • Hyukbean Kwon,
  • Ui-Joung Youn,
  • Joo-Won Nam,
  • Sung-Hak Kim and
  • Hyukjae Choi
  • + 1 author

5 December 2025

The journal retracts the article titled “Anticancer Activity of 2-O-Caffeoyl Alphitolic Acid Extracted from the Lichen, Usnea barbata 2017-KL-10” [...]

  • Article
  • Open Access

5 December 2025

Bismaleimide–triazine (BT) resins are widely utilized in various applications, with ongoing efforts to enhance their performance. In this work, a partially epoxidized polyhedral oligomeric silsesquioxane (PEOVS) containing vinyl and epoxy group...

  • Article
  • Open Access

Synthesis of Substituted 1H-Phenalen-1-ones and Nitrogen-Containing Heterocyclic Analogues as Potential Anti-Plasmodial Agents

  • Teresa Abad-Grillo,
  • Grant McNaughton-Smith,
  • Mónica Blanco Freijo,
  • David Gutiérrez and
  • Ninoska Flores

5 December 2025

Given the known biological activity of both natural and synthetic substituted 1H-phenalen-1-ones, the generation of a small chemically and structurally diverse 1H-phenalen-1-one-based library of compounds was warranted. Herein, we have synthesized se...

  • Article
  • Open Access

5 December 2025

Oral squamous cell carcinoma (OSCC) is an aggressive malignancy characterized by high invasiveness and poor prognosis. This study investigated the anticancer mechanisms of eupatilin, a pharmacologically active flavonoid derived from Artemisia species...

  • Article
  • Open Access

Profile of Free and Conjugated Phenolic Compounds of Okra Pods Subjected to High-Humidity Hot-Air Impingement Blanching (HHAIB)

  • Danuta Zielińska,
  • Natalia Płatosz,
  • Kacper Górski,
  • Magdalena Zielińska,
  • Hong-Wei Xiao and
  • Henryk Zieliński

5 December 2025

The profiles of free, ester-bound, and glycoside-bound phenolic compounds in okra pods (OP) subjected to high-humidity hot-air impingement blanching (HHAIB) for up to 120 s were analyzed using a micro-HPLC-QTRAP/MS/MS method. Fourteen phenolic acids...

  • Article
  • Open Access

Quantum Smell: Tunneling Mechanisms in Olfaction

  • Dominik Szczȩśniak,
  • Ewa A. Drzazga-Szczȩśniak,
  • Adam Z. Kaczmarek and
  • Sabre Kais

5 December 2025

The mechanism by which odorants are recognized by olfactory receptors remains primarily unresolved. While charge transport is believed to play a significant role, its precise nature is still unclear. Here, we present a novel perspective by exploring...

  • Article
  • Open Access

New Dimethylpyridine-3-Carboxamide Derivatives as MMP-13 Inhibitors with Anticancer Activity

  • Remigiusz Płaczek,
  • Tomasz Janek,
  • Małgorzata Strzelecka,
  • Aleksandra Kotynia,
  • Piotr Świątek and
  • Żaneta Czyżnikowska

5 December 2025

A series of dimethylpyridine-3-carboxamide derivatives was designed as potential, selective, non-zinc chelating inhibitors of matrix metalloproteinase 13 (MMP-13), and subsequently synthesized. The identity of the obtained compounds was confirmed by...

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Molecules - ISSN 1420-3049