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Molecules, Volume 30, Issue 18

September-2 2025 - 182 articles

Cover Story: Antibiotic overuse and drug-resistant strains are escalating global mortality associated with tumors and infectious diseases. This critical public health threat urgently necessitates advanced strategies for detecting and treating cancers and pathogenic microorganisms. Conjugated oligomers, formed by a limited number of repeating conjugated units linked through covalent bonds, exhibit high potential for various applications in biological monitoring and disease diagnosis due to their controllable molecular weight, precise molecular structure, and excellent photostability. In this review, we summarize recent advancements in the application of conjugated oligomers in imaging, cancer therapy, and antibacterial treatment. Furthermore, this article critically examines challenges in their biological application, underscoring the need for continued innovation. View this paper
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Articles (182)

  • Review
  • Open Access
1,974 Views
26 Pages

Botany, Ethnomedicinal Uses, Biological Activities, Phytochemistry, and Technological Applications of Morinda citrifolia Plants

  • José Adão Carvalho Nascimento Júnior,
  • Anamaria Mendonça Santos,
  • Ana Maria Santos Oliveira,
  • Cláudio Carvalho Santana Júnior,
  • Mairim Russo Serafini,
  • Jullyana de Souza Siqueira Quintans,
  • Laurent Picot,
  • Irwin Rose Alencar de Menezes and
  • Lucindo José Quintans-Júnior

21 September 2025

Morinda citrifolia L., known as noni, is a tropical plant belonging to the Rubiaceae family and is widely used in traditional medicine for its therapeutic properties. This review compiles botanical, ethnomedicinal, phytochemical, and pharmacological...

  • Article
  • Open Access
800 Views
16 Pages

21 September 2025

Olive leaves, a significant source of agri-food waste, can be valorized as feedstock in biorefineries due to their high content of antioxidant compounds, mainly polyphenols. This study aims to valorize olive leaves through an efficient solid/liquid e...

  • Review
  • Open Access
1,038 Views
25 Pages

The Role of Metallodrugs in Enhancing Neuroendocrine Neoplasm Therapies: The Promising Anticancer Potential of Ruthenium-Based Complexes

  • Erika Stefàno,
  • Federica De Castro,
  • Asjad Ali,
  • Michele Benedetti and
  • Francesco Paolo Fanizzi

21 September 2025

Neuroendocrine neoplasms (NENs) represent a small and heterogeneous group of tumors that share a common phenotype, originating from cells within the endocrine and nervous systems. Metallodrugs have had a significant impact on the treatment of NENs, a...

  • Article
  • Open Access
879 Views
14 Pages

The Effect of Two Preservation Techniques on the Yield, Percentage Solids, Electrophoretic Profile, Gelatinolytic Activity, and Brine Shrimp Lethality of Bitis arietans Venom

  • Mitchel Okumu,
  • Anna Nieczaj,
  • Farhan Hassan,
  • Selline Ooko,
  • Ebrahim Sande,
  • Rosa Chinheya,
  • Jacqueline Manjia and
  • Aleksandra Bocian

21 September 2025

This study compared the yield, percentage solids, electrophoretic profile, gelatinolytic activity, and brine shrimp lethality of Bitis arietans venom prepared using freeze-drying and desiccator drying. Bitis arietans venom was collected from snakes a...

  • Article
  • Open Access
770 Views
15 Pages

21 September 2025

The main objective of the study was to choose the best salicylic acid-based monomers through in silico research to improve the antibacterial effects of dental prostheses, refine the synthesis process of such monomers, and examine their antibacterial...

  • Review
  • Open Access
1,275 Views
17 Pages

21 September 2025

Neurodegenerative diseases, including Parkinson’s disease, Alzheimer’s disease, multiple sclerosis, and Huntington’s disease, represent unmet medical and social needs. Still, no definitive cure exists for these illnesses, hence a th...

  • Article
  • Open Access
3,325 Views
14 Pages

Hepatotoxicity and Antimicrobial Resistance to Amoxicillin and Amoxicillin/Clavulanic Acid: Data Analysis from EudraVigilance

  • Ilaria Ammendolia,
  • Carmen Mannucci,
  • Emanuela Esposito,
  • Gioacchino Calapai,
  • Mariaconcetta Currò,
  • Paola Midiri,
  • Luigi Cardia and
  • Fabrizio Calapai

21 September 2025

Amoxicillin is widely prescribed, either as a monotherapy or in combination with clavulanic acid, with its therapeutic indications including a broad range of infections. Its combination with clavulanic acid maintains its known activity against strain...

  • Article
  • Open Access
861 Views
20 Pages

20 September 2025

Copper is an important environmental pollutant that poses a significant threat to human health and environmental safety. Therefore, the development of methods for detecting Cu2+ is of great significance. A novel fluorometric/colorimetric dual-mode se...

  • Article
  • Open Access
741 Views
16 Pages

20 September 2025

Photocatalytic hydrogen evolution from water is a sustainable approach to producing clean energy and promoting sustainable development. However, the low efficiency of photocatalysts under visible light and even near-infrared irradiation remains the c...

  • Article
  • Open Access
704 Views
31 Pages

20 September 2025

Sirtuin 5 is an NAD+-dependent lysine deacylase that is involved in various biological processes and has emerged as a promising target for pharmaceutical therapies. The development of highly potent and subtype-selective sirtuin 5 inhibitors for their...

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Molecules - ISSN 1420-3049