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Molecules, Volume 26, Issue 21

November-1 2021 - 431 articles

Cover Story: Phosphate and sulfate ions pose a substantial risk to aquatic life. Further, recovery of phosphorous is a vital challenge as it is a finite resource and is indispensable for agriculture. Thus, efficient removal and recovery is essential for aqueous ecosystems and the economy. Poly(melamine-co-formaldehyde) (PMF) with its high chemical resistance and its high amount of nitrogen functionalities represents an ideal adsorbent material. Here, PMF was synthesized in the form of mesoporous particles yielding specific surface areas up to 409 m2/g. Different amounts of silica nanospheres were utilized as a hard template. The obtained porous PMF particles achieved extremely high adsorption capacities for sulfate and phosphate ions. Selective adsorption of sulfate was achieved for hybrid SiO2 PMF particles.
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Articles (431)

  • Article
  • Open Access
10 Citations
2,753 Views
13 Pages

8 November 2021

Two rare guanidine-type alkaloids, Buthutin A (1) and Buthutin B (2), along with two other compounds (3, 4), were isolated from Buthus martensii Karsch, and determined using extensive spectroscopic data analysis and high resolution-mass spectrometry....

  • Perspective
  • Open Access
6 Citations
3,670 Views
7 Pages

8 November 2021

A perspective on the use of heterogeneous catalysis to drive the waste-to-pharma concept is provided in this contribution based on the conversion of furanics to active pharmaceutical ingredients (APIs). The provided overview of the concept in this pe...

  • Article
  • Open Access
36 Citations
4,121 Views
11 Pages

Metabolomics Provides A Novel Interpretation of the Changes in Main Compounds during Black Tea Processing through Different Drying Methods

  • Fei Ye,
  • Xiaoyan Qiao,
  • Anhui Gui,
  • Shengpeng Wang,
  • Panpan Liu,
  • Xueping Wang,
  • Jin Teng,
  • Lin Zheng,
  • Lin Feng and
  • Hanshan Han
  • + 2 authors

8 November 2021

This study aimed to compare the effect of hot roller (HR) drying and hot air (HA) drying on the sensory evaluation, chemical quality, antioxidant activity, and metabolic profile of Yihong Congou black tea processed from E’cha NO1. The Yihong Congou b...

  • Article
  • Open Access
4 Citations
3,187 Views
15 Pages

Finding the First Potential Inhibitors of Shikimate Kinase from Methicillin Resistant Staphylococcus aureus through Computer-Assisted Drug Design

  • Lluvia Rios-Soto,
  • Alfredo Téllez-Valencia,
  • Erick Sierra-Campos,
  • Mónica Valdez-Solana,
  • Jorge Cisneros-Martínez,
  • Marcelo Gómez Palacio-Gastélum,
  • Adriana Castillo-Villanueva and
  • Claudia Avitia-Domínguez

8 November 2021

Methicillin-resistant Staphylococcus aureus (MRSA) is an important threat as it causes serious hospital and community acquired infections with deathly outcomes oftentimes, therefore, development of new treatments against this bacterium is a priority....

  • Article
  • Open Access
17 Citations
5,726 Views
22 Pages

Proteomic and Bioinformatic Analysis of Decellularized Pancreatic Extracellular Matrices

  • Ming Hu,
  • Huanjing Bi,
  • Deana Moffat,
  • Margaret Blystone,
  • Lillian DeCostanza,
  • Tchilabalo Alayi,
  • Kaiming Ye,
  • Yetrib Hathout and
  • Sha Jin

8 November 2021

Tissue microenvironments are rich in signaling molecules. However, factors in the tissue matrix that can serve as tissue-specific cues for engineering pancreatic tissues have not been thoroughly identified. In this study, we performed a comprehensive...

  • Article
  • Open Access
24 Citations
4,778 Views
18 Pages

Chloroquine Potentiates the Anticancer Effect of Pterostilbene on Pancreatic Cancer by Inhibiting Autophagy and Downregulating the RAGE/STAT3 Pathway

  • Rong-Jane Chen,
  • Yi-Jhen Lyu,
  • Yu-Ying Chen,
  • Yen-Chien Lee,
  • Min-Hsiung Pan,
  • Yuan-Soon Ho and
  • Ying-Jan Wang

8 November 2021

The treatment of pancreatic ductal adenocarcinoma (PDAC) remains a huge challenge, because pro-survival signaling pathways—such as the receptor for advanced glycation end products (RAGE)/signal transducer and activator of transcription 3 (STAT3) path...

  • Article
  • Open Access
17 Citations
4,314 Views
28 Pages

Structural Optimization and Biological Activity of Pyrazole Derivatives: Virtual Computational Analysis, Recovery Assay and 3D Culture Model as Potential Predictive Tools of Effectiveness against Trypanosoma cruzi

  • Lorraine Martins Rocha Orlando,
  • Guilherme Curty Lechuga,
  • Leonardo da Silva Lara,
  • Byanca Silva Ferreira,
  • Cynthia Nathalia Pereira,
  • Rafaela Corrêa Silva,
  • Maurício Silva dos Santos and
  • Mirian Claudia S. Pereira

8 November 2021

Chagas disease, a chronic and silent disease caused by Trypanosoma cruzi, is currently a global public health problem. The treatment of this neglected disease relies on benznidazole and nifurtimox, two nitroheterocyclic drugs that show limited effica...

  • Article
  • Open Access
5 Citations
2,896 Views
21 Pages

8 November 2021

This study describes for the first time the comprehensive characterization of tetrapyrrole cofactor biosynthetic pathways developed for bacterial community (BC) inhabiting shale rock. Based on the genomic and proteomic metadata, we have detailed the...

  • Review
  • Open Access
68 Citations
6,976 Views
13 Pages

Roles of the 2-Oxoglutarate-Dependent Dioxygenase Superfamily in the Flavonoid Pathway: A Review of the Functional Diversity of F3H, FNS I, FLS, and LDOX/ANS

  • Yueyue Wang,
  • Yufeng Shi,
  • Kaiyuan Li,
  • Dong Yang,
  • Nana Liu,
  • Lingjie Zhang,
  • Lei Zhao,
  • Xinfu Zhang,
  • Yajun Liu and
  • Liping Gao
  • + 2 authors

8 November 2021

The 2-oxoglutarate-dependent dioxygenase (2-OGD) superfamily is one of the largest protein families in plants. The main oxidation reactions they catalyze in plants are hydroxylation, desaturation, demethylation, epimerization, and halogenation. Four...

  • Article
  • Open Access
12 Citations
2,896 Views
16 Pages

8 November 2021

Plant-derived antimicrobial agents have adequate antimicrobial effects on food-borne pathogens, which can be used as food preservatives. The purpose of this study was to evaluate the antibacterial mechanism of chlorogenic acid (CA) against Yersinia e...

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Molecules - ISSN 1420-3049Creative Common CC BY license