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Molecules, Volume 25, Issue 3

February-1 2020 - 334 articles

Cover Story: Oligonucleotides, such as peptide nucleic acid (PNA), designed to block the synthesis of essential bacterial proteins, could be used as antibacterials. The limitation precluding PNA use is that bacterial cells do not uptake PNA. Thus, both PNA carriers and new targets in bacteria have been extensively searched for. The cover presents carriers of PNA to bacteria and possible targets for sequence-specific inhibition by PNA. The delivery strategies comprise covalent conjugation of PNA with cell-penetrating peptides (CPP) and with vitamin B12, as well as complementary base pairing between PNA and DNA to form a tetrahedral DNA nanostructure (TDN). PNA targets tested in Gram-negative bacteria include mRNA, ribosome (small 30S and large 50S subunit), and toxin–antitoxin (TA) systems. View this paper.
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Articles (334)

  • Article
  • Open Access
3 Citations
4,200 Views
11 Pages

10 February 2020

p-Coumaric acid (pCA) and trans-ferulic acid (TFA) were co-crystallised with 2-amino-4-picoline (2A4MP) and 2-amino-6-picoline (2A6MP) producing organic salts of (pCA−)(2A4MP+) (1), (pCA̶ )(2A6MP+) (2) and (TFA̶ )(2A4MP+)·( 3 2 H...

  • Review
  • Open Access
66 Citations
10,529 Views
18 Pages

10 February 2020

Nowadays, food packaging is a crucial tool for preserving food quality and has become an inseparable part of our daily life. Strong consumer demand and market trends enforce more advanced and creative forms of food packaging. New packaging developmen...

  • Article
  • Open Access
77 Citations
6,898 Views
12 Pages

Melatonin Accumulation in Sweet Cherry and Its Influence on Fruit Quality and Antioxidant Properties

  • Hui Xia,
  • Yanqiu Shen,
  • Tian Shen,
  • Xin Wang,
  • Xuefeng Zhang,
  • Peng Hu,
  • Dong Liang,
  • Lijin Lin,
  • Honghong Deng and
  • Jin Wang
  • + 2 authors

10 February 2020

Although the effects of melatonin on plant abiotic and biotic stress resistance have been explored in recent decades, the accumulation of endogenous melatonin in plants and its influence on fruit quality remains unclear. In the present study, melaton...

  • Article
  • Open Access
35 Citations
5,378 Views
10 Pages

Effect of Polyvinyl Alcohol on the Rheological Properties of Cement Mortar

  • Fang Liu,
  • Baomin Wang,
  • Yunqing Xing,
  • Kunkun Zhang and
  • Wei Jiang

10 February 2020

Polyvinyl alcohol (PVA) is a kind of water-soluble polymer, which has been widely used in different industries due to its excellent mechanical and chemical properties. In this paper, the effects of polyvinyl alcohol with different hydrolysis and poly...

  • Article
  • Open Access
13 Citations
6,302 Views
15 Pages

An Optimised Di-Boronate-ChemMatrix Affinity Chromatography to Trap Deoxyfructosylated Peptides as Biomarkers of Glycation

  • Monika Kijewska,
  • Francesca Nuti,
  • Magdalena Wierzbicka,
  • Mateusz Waliczek,
  • Patrycja Ledwoń,
  • Agnieszka Staśkiewicz,
  • Feliciana Real-Fernandez,
  • Giuseppina Sabatino,
  • Paolo Rovero and
  • Piotr Stefanowicz
  • + 2 authors

10 February 2020

We report herein a novel ChemMatrix® Rink resin functionalised with two phenylboronate (PhB) moieties linked on the N-α and N-ε amino functions of a lysine residue to specifically capture deoxyfructosylated peptides, compared to dif...

  • Article
  • Open Access
70 Citations
8,500 Views
20 Pages

An Interpenetrating Alginate/Gelatin Network for Three-Dimensional (3D) Cell Cultures and Organ Bioprinting

  • Qiuhong Chen,
  • Xiaohong Tian,
  • Jun Fan,
  • Hao Tong,
  • Qiang Ao and
  • Xiaohong Wang

10 February 2020

Crosslinking is an effective way to improve the physiochemical and biochemical properties of hydrogels. In this study, we describe an interpenetrating polymer network (IPN) of alginate/gelatin hydrogels (i.e., A-G-IPN) in which cells can be encapsula...

  • Article
  • Open Access
40 Citations
6,310 Views
15 Pages

10 February 2020

This study aimed to investigate whether quercetin exerts anticancer effects on oral squamous cell carcinoma (OSCC) cell lines and to elucidate its mechanism of action. These anticancer effects in OSCC cells were assessed using an MTT assay, flow cyto...

  • Article
  • Open Access
45 Citations
8,822 Views
18 Pages

10 February 2020

Coconut oil-in-water emulsions were prepared using three polysaccharides: Dendrobium officinale polysaccharide (DOP), propylene glycol alginate (PGA), gum arabic (GA) and their polysaccharide complexes as emulsifiers. The effects of the ratio of the...

  • Article
  • Open Access
5 Citations
4,871 Views
12 Pages

Direct Recovery of the Rare Earth Elements Using a Silk Displaying a Metal-Recognizing Peptide

  • Nobuhiro Ishida,
  • Takaaki Hatanaka,
  • Yoichi Hosokawa,
  • Katsura Kojima,
  • Tetsuya Iizuka,
  • Hidetoshi Teramoto,
  • Hideki Sezutsu and
  • Tsunenori Kameda

10 February 2020

Rare earth elements (RE) are indispensable metallic resources in the production of advanced materials; hence, a cost- and energy-effective recovery process is required to meet the rapidly increasing RE demand. Here, we propose an artificial RE recove...

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Molecules - ISSN 1420-3049