Next Article in Journal
Therapeutic Potential of Flavonoids in Pain and Inflammation: Mechanisms of Action, Pre-Clinical and Clinical Data, and Pharmaceutical Development
Next Article in Special Issue
Silk Particle Production Based on Silk/PVA Phase Separation Using a Microfabricated Co-flow Device
Previous Article in Journal
Stabilizing the Oil-in-Water Emulsions Using the Mixtures of Dendrobium Officinale Polysaccharides and Gum Arabic or Propylene Glycol Alginate
Previous Article in Special Issue
Spider Silk for Tissue Engineering Applications
Open AccessArticle

Direct Recovery of the Rare Earth Elements Using a Silk Displaying a Metal-Recognizing Peptide

1
Strategic Research Division, TOYOTA Central R&D Labs, Inc., 41-1, Yokomichi, Nagakute, Aichi 480-1192, Japan
2
Silk Materials Research Unit, Division of Biotechnology, Institute of Agrobiological Sciences, National Agriculture and Food Research Organization (NARO), 1-2, Owashi, Tsukuba, Ibaraki 305-8634, Japan
3
Transgenic Silkworm Research Unit, Division of Biotechnology, Institute of Agrobiological Sciences, National Agriculture and Food Research Organization (NARO), 1-2, Owashi, Tsukuba, Ibaraki 305-8634, Japan
*
Author to whom correspondence should be addressed.
Academic Editors: Giuseppe Cirillo and Yasumoto Nakazawa
Molecules 2020, 25(3), 761; https://doi.org/10.3390/molecules25030761
Received: 28 December 2019 / Revised: 15 January 2020 / Accepted: 4 February 2020 / Published: 10 February 2020
(This article belongs to the Special Issue Silk Fibroin Materials)
Rare earth elements (RE) are indispensable metallic resources in the production of advanced materials; hence, a cost- and energy-effective recovery process is required to meet the rapidly increasing RE demand. Here, we propose an artificial RE recovery approach that uses a functional silk displaying a RE-recognizing peptide. Using the piggyBac system, we constructed a transgenic silkworm in which one or two copies of the gene coding for the RE-recognizing peptide (Lamp1) was fused with that of the fibroin L (FibL) protein. The purified FibL-Lamp1 fusion protein from the transgenic silkworm was able to recognize dysprosium (Dy3+), a RE, under physiological conditions. This method can also be used with silk from which sericin has been removed. Furthermore, the Dy-recovery ability of this silk was significantly improved by crushing the silk. Our simple approach is expected to facilitate the direct recovery of RE from an actual mixed solution of metal ions, such as seawater and industrial wastewater, under mild conditions without additional energy input. View Full-Text
Keywords: rare earth elements; dysprosium; transgenic silkworm; rare earth recovery rare earth elements; dysprosium; transgenic silkworm; rare earth recovery
Show Figures

Graphical abstract

MDPI and ACS Style

Ishida, N.; Hatanaka, T.; Hosokawa, Y.; Kojima, K.; Iizuka, T.; Teramoto, H.; Sezutsu, H.; Kameda, T. Direct Recovery of the Rare Earth Elements Using a Silk Displaying a Metal-Recognizing Peptide. Molecules 2020, 25, 761.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop