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Molecules, Volume 23, Issue 5

May 2018 - 253 articles

Cover Story: The image shows the disproportionation reaction of Sn(I)Cl yields in the presence of LiGe(SiMe3)3; the metalloid tin clusters Sn10[Ge(SiMe3)3]6, {Sn10[Ge(SiMe3)3]5} and {Sn10[Ge(SiMe3)3]4}2−. All clusters are structurally similar to their Si(SiMe3)3 derivatives, but show different stabilities in solution and different electronic situations for the tin atoms, as shown by 119mSn Mössbauer spectroscopy, giving a first insight into the influence of the substituent on the properties of metalloid tin cluster compounds. View this paper
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Articles (253)

  • Article
  • Open Access
30 Citations
5,376 Views
17 Pages

The calculation of the surface tension of ordinary organic and ionic liquids, based on a computer algorithm applying a refined group-additivity method, is presented. The refinement consists of the complete breakdown of the molecules into their consti...

  • Article
  • Open Access
12 Citations
4,324 Views
9 Pages

Reaction between pyrogallol and benzaldehyde results in a conformational mixture of C-tetra(phenyl)pyrogallol[4]arene (crown and chair). The conformer mixture was separated using crystallization procedures and the structures were determined using FTI...

  • Feature Paper
  • Review
  • Open Access
56 Citations
11,116 Views
29 Pages

Nutraceuticals in Periodontal Health: A Systematic Review on the Role of Vitamins in Periodontal Health Maintenance

  • Alfonso Varela-López,
  • María D. Navarro-Hortal,
  • Francesca Giampieri,
  • Pedro Bullón,
  • Maurizio Battino and
  • José L. Quiles

Periodontal disease, a relevant public health problem worldwide, is generally considered a common pathology of elderly people. In this respect, there is agreement about that nutritional status may be a modifying factor in the progression and healing...

  • Article
  • Open Access
73 Citations
6,850 Views
15 Pages

The microencapsulation of maqui juice by spray-drying and freeze-drying was studied as a strategy to protect anthocyanins in new food formulations in order to improve the anthocyanin retention before consumption and the bioaccessibility. It is well k...

  • Article
  • Open Access
104 Citations
9,450 Views
15 Pages

Cyclodextrins (CDs) are cyclic oligosaccharides; the most common CDs contain six, seven, or eight glucose units called α-CDs, β-CDs, and γ-CDs, respectively. The use of CDs in biomedical research is increasing due to their ability to...

  • Article
  • Open Access
20 Citations
6,646 Views
15 Pages

Plasma Pharmacokinetic Determination of Canagliflozin and Its Metabolites in a Type 2 Diabetic Rat Model by UPLC-MS/MS

  • Song-tao Dong,
  • Hui-min Niu,
  • Yin Wu,
  • Jia-lei Jiang,
  • Ying Li,
  • Kun-yu Jiang,
  • Xin Wang,
  • Mao-fan Zhang,
  • Ming-feng Han and
  • Sheng-nan Meng

Canagliflozin is a novel, orally selective inhibitor of sodium-dependent glucose co-transporter-2 (SGLT2) for the treatment of patients with type 2 diabetes mellitus. In this study, a sensitive and efficient UPLC-MS/MS method for the quantification o...

  • Article
  • Open Access
174 Citations
34,039 Views
22 Pages

Quality Traits of “Cannabidiol Oils”: Cannabinoids Content, Terpene Fingerprint and Oxidation Stability of European Commercially Available Preparations

  • Radmila Pavlovic,
  • Giorgio Nenna,
  • Lorenzo Calvi,
  • Sara Panseri,
  • Gigliola Borgonovo,
  • Luca Giupponi,
  • Giuseppe Cannazza and
  • Annamaria Giorgi

Cannabidiol (CBD)-based oil preparations are becoming extremely popular, as CBD has been shown to have beneficial effects on human health. CBD-based oil preparations are not unambiguously regulated under the European legislation, as CBD is not consid...

  • Article
  • Open Access
1 Citations
6,232 Views
8 Pages

Improved Synthesis of N-Methylcadaverine

  • Kayla N. Anderson,
  • Shiva Moaven,
  • Daniel K. Unruh,
  • Anthony F. Cozzolino and
  • John C. D’Auria

Alkaloids compose a large class of natural products, and mono-methylated polyamines are a common intermediate in their biosynthesis. In order to evaluate the role of selectively methylated natural products, synthetic strategies are needed to prepare...

  • Article
  • Open Access
16 Citations
6,541 Views
11 Pages

Mesoionic pyrido[1,2-α]pyrimidinone derivatives containing a neonicotinoid moiety were designed, synthesized, and evaluated for their insecticidal activity. Some of the title compounds showed remarkable insecticidal properties against Aphis cra...

  • Article
  • Open Access
20 Citations
5,117 Views
13 Pages

Sterol Composition of Clinically Relevant Mucorales and Changes Resulting from Posaconazole Treatment

  • Christoph Müller,
  • Thomas Neugebauer,
  • Patrizia Zill,
  • Cornelia Lass-Flörl,
  • Franz Bracher and
  • Ulrike Binder

Mucorales are fungi with increasing importance in the clinics. Infections take a rapidly progressive course resulting in high mortality rates. The ergosterol biosynthesis pathway and sterol composition are of interest, since they are targeted by curr...

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Molecules - ISSN 1420-3049