Pathophysiology of Aging and Age-related Diseases

Dear Colleagues,

Oxidative stress is generated daily; however, when it exceeds the capacity of self-limiting mechanism, it causes decompensation of the tissue/organ function. The mechanism may be involved in tissue/organ functional disorders during physiological aging and pathogenesis of age-related diseases. In order to develop novel therapeutic approaches for treating and preventing age-related diseases, as well as preserve healthy aging, both of which lead to a better quality of life, this Interdisciplinary Topic pays special attention to the molecular mechanisms, biomarkers, epidemiology, therapeutic proof of concept, and clinical trials which could open up a new era in the medical fields of aging and age-related diseases.

We invite you to contribute an original paper or a review paper on recent novel concepts based on basic and/or clinical research to understand mechanisms of age-related diseases, metabolic syndrome, neurodegeneration, longevity, and so on.

Prof. Dr. Yoko Ozawa
Prof. Dr. Yasumichi Arai
Dr. Sumihiro Maeda
Topic Editors