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10 Results Found

  • Review
  • Open Access
117 Citations
12,180 Views
22 Pages

Cardiovascular Stents: A Review of Past, Current, and Emerging Devices

  • Alexandru Scafa Udriște,
  • Adelina-Gabriela Niculescu,
  • Alexandru Mihai Grumezescu and
  • Elisabeta Bădilă

12 May 2021

One of the leading causes of morbidity and mortality worldwide is coronary artery disease, a condition characterized by the narrowing of the artery due to plaque deposits. The standard of care for treating this disease is the introduction of a stent...

  • Review
  • Open Access
34 Citations
8,793 Views
16 Pages

Drug-Eluting Stents: Technical and Clinical Progress

  • Maciej Koźlik,
  • Jan Harpula,
  • Piotr J. Chuchra,
  • Magdalena Nowak,
  • Wojciech Wojakowski and
  • Paweł Gąsior

Drug-eluting stents (DES) demonstrated superior efficacy when compared to bare metal stents and plain-old balloon angioplasty and are nowadays used in almost all percutaneous revascularization procedures. The design of the stent platforms is constant...

  • Review
  • Open Access
44 Citations
9,113 Views
28 Pages

Coatings for Cardiovascular Stents—An Up-to-Date Review

  • Alexandru Scafa Udriște,
  • Alexandra Cristina Burdușel,
  • Adelina-Gabriela Niculescu,
  • Marius Rădulescu and
  • Alexandru Mihai Grumezescu

16 January 2024

Cardiovascular diseases (CVDs) increasingly burden health systems and patients worldwide, necessitating the improved awareness of current treatment possibilities and the development of more efficient therapeutic strategies. When plaque deposits narro...

  • Article
  • Open Access
6 Citations
2,688 Views
15 Pages

An Innovative Stereolithography 3D Tubular Method for Ultrathin Polymeric Stent Manufacture: The Effect of Process Parameters

  • Aniol Bosch,
  • Enric Casanova-Batlle,
  • Iuliana Constantin,
  • Carles Rubio,
  • Joaquim Ciurana and
  • Antonio J. Guerra

1 November 2023

In the last decades, researchers have been developing bioresorbable stents (BRS) to overcome the long-term complications of drug-eluting stents (DES). However, BRS technology still presents challenging limitations in terms of manufacturing, materials...

  • Article
  • Open Access
7 Citations
3,312 Views
18 Pages

22 April 2023

Cardiovascular diseases are the leading cause of death globally. Vascular implants, such as stents, are required to treat arterial stenosis or dilatation. The development of innovative stent materials and coatings, as well as novel preclinical testin...

  • Review
  • Open Access
89 Citations
14,776 Views
19 Pages

The technology of percutaneous coronary intervention (PCI) is constantly being refined in order to overcome the shortcomings of present day technologies. Even though current generation metallic drug-eluting stents (DES) perform very well in the short...

  • Review
  • Open Access
21 Citations
3,449 Views
18 Pages

19 February 2025

The sector of 4D printing represents a new frontier in additive manufacturing that allows for a material’s capability to adapt and respond to various stimuli, such as thermal transitions, humidity, and pH levels. The adaptability of such a mate...

  • Review
  • Open Access
629 Views
25 Pages

Traditional drug delivery methods for gastrointestinal diseases, including oral and systemic administration, often suffer from degradation, inadequate mucosal absorption, and off-target toxicity. Consequently, these methods result in low bioavailabil...

  • Article
  • Open Access
14 Citations
5,087 Views
16 Pages

A Multilayer Functionalized Drug-Eluting Balloon for Treatment of Coronary Artery Disease

  • Hak-Il Lee,
  • Won-Kyu Rhim,
  • Eun-Young Kang,
  • Bogyu Choi,
  • Jun-Hyeok Kim and
  • Dong-Keun Han

Drug-eluting balloons (DEBs) have been mostly exploited as an interventional remedy for treating atherosclerosis instead of cardiovascular stents. However, the therapeutic efficacy of DEB is limited due to their low drug delivery capability to the di...

  • Review
  • Open Access
513 Views
16 Pages

Bioresorbable Scaffolds for Coronary Revascularization: From Concept to Clinical Maturity

  • Angeliki Bourazana,
  • Alexandros Briasoulis,
  • Christos Kourek,
  • Toshiki Kuno,
  • Ioannis Leventis,
  • Chris Pantsios,
  • Vasiliki Androutsopoulou,
  • Kyriakos Spiliopoulos,
  • Grigorios Giamouzis and
  • Andrew Xanthopoulos
  • + 1 author

Over the past decades, coronary revascularization has evolved dramatically with the introduction of bioresorbable scaffolds (BRSs), designed to provide temporary vessel support, elute antiproliferative drugs, and then fully resorb, ideally restoring...