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7 Results Found

  • Review
  • Open Access
22 Citations
6,530 Views
21 Pages

Microbial water quality is of vital importance for human, animal, and environmental health. Notably, pathogenically contaminated water can result in serious health problems, such as waterborne outbreaks, which have caused huge economic and social los...

  • Review
  • Open Access
101 Citations
22,181 Views
66 Pages

Advanced Methods for Natural Products Discovery: Bioactivity Screening, Dereplication, Metabolomics Profiling, Genomic Sequencing, Databases and Informatic Tools, and Structure Elucidation

  • Susana P. Gaudêncio,
  • Engin Bayram,
  • Lada Lukić Bilela,
  • Mercedes Cueto,
  • Ana R. Díaz-Marrero,
  • Berat Z. Haznedaroglu,
  • Carlos Jimenez,
  • Manolis Mandalakis,
  • Florbela Pereira and
  • Deniz Tasdemir
  • + 1 author

19 May 2023

Natural Products (NP) are essential for the discovery of novel drugs and products for numerous biotechnological applications. The NP discovery process is expensive and time-consuming, having as major hurdles dereplication (early identification of kno...

  • Article
  • Open Access
35 Citations
6,109 Views
15 Pages

Integrated Analysis of microRNA and mRNA Expression Profiles: An Attempt to Disentangle the Complex Interaction Network in Attention Deficit Hyperactivity Disorder

  • Nicoletta Nuzziello,
  • Francesco Craig,
  • Marta Simone,
  • Arianna Consiglio,
  • Flavio Licciulli,
  • Lucia Margari,
  • Giorgio Grillo,
  • Sabino Liuni and
  • Maria Liguori

22 October 2019

Attention Deficit Hyperactivity Disorder (ADHD) is a childhood-onset neurodevelopmental disorder, whose etiology and pathogenesis are still largely unknown. In order to uncover novel regulatory networks and molecular pathways possibly related to ADHD...

  • Review
  • Open Access
47 Citations
11,732 Views
18 Pages

Analyzing Modern Biomolecules: The Revolution of Nucleic-Acid Sequencing – Review

  • Gabriel Dorado,
  • Sergio Gálvez,
  • Teresa E. Rosales,
  • Víctor F. Vásquez and
  • Pilar Hernández

28 July 2021

Recent developments have revolutionized the study of biomolecules. Among them are molecular markers, amplification and sequencing of nucleic acids. The latter is classified into three generations. The first allows to sequence small DNA fragments. The...

  • Review
  • Open Access
53 Citations
9,144 Views
31 Pages

18 June 2022

Antarctica represents a unique environment, both due to the extreme meteorological and geological conditions that govern it and the relative isolation from human influences that have kept its environment largely undisturbed. However, recent trends in...

  • Editorial
  • Open Access
5 Citations
2,152 Views
3 Pages

23 February 2023

Next-generation sequencing (NGS), also known as high-throughput sequencing (HTS), is a commonly used term to represent a set of DNA sequencing technologies that have been in use for almost two decades [...]

  • Article
  • Open Access
3 Citations
1,357 Views
13 Pages

7 February 2025

High-throughput sequencing (HTS) has revolutionized phytopathology by overcoming many limitations of traditional diagnostic methods, as it permits precise pathogen monitoring, identification, and control, with ribosomal DNA (rDNA) regions serving as...