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9 Results Found

  • Article
  • Open Access
27 Citations
7,800 Views
8 Pages

Quality of Life in Patients with Gluten Neuropathy: A Case-Controlled Study

  • Panagiotis Zis,
  • Ptolemaios Georgios Sarrigiannis,
  • Dasappaiah Ganesh Rao and
  • Marios Hadjivassiliou

23 May 2018

Background: Gluten neuropathy (GN) is defined as an otherwise idiopathic peripheral neuropathy in the presence of serological evidence of gluten sensitivity (positive native gliadin antibodies and/or transglutaminase or endomysium antibodies). We aim...

  • Feature Paper
  • Review
  • Open Access
69 Citations
13,114 Views
14 Pages

Neurological Manifestations of Neuropathy and Ataxia in Celiac Disease: A Systematic Review

  • Elizabeth S. Mearns,
  • Aliki Taylor,
  • Kelly J. Thomas Craig,
  • Stefanie Puglielli,
  • Allie B. Cichewicz,
  • Daniel A. Leffler,
  • David S. Sanders,
  • Benjamin Lebwohl and
  • Marios Hadjivassiliou

12 February 2019

Celiac disease (CD) is an immune-mediated gastrointestinal disorder driven by innate and adaptive immune responses to gluten. Patients with CD are at an increased risk of several neurological manifestations, frequently peripheral neuropathy and glute...

  • Review
  • Open Access
36 Citations
8,871 Views
17 Pages

The Neuropathology of Gluten-Related Neurological Disorders: A Systematic Review

  • Maxine D Rouvroye,
  • Panagiotis Zis,
  • Anne-Marie Van Dam,
  • Annemieke J.M. Rozemuller,
  • Gerd Bouma and
  • Marios Hadjivassiliou

20 March 2020

Gluten-related neurological disorders (GRND) represent a spectrum of neurological manifestations that are triggered by gluten. In coeliac disease, a T-cell mediated enteropathy is triggered by gluten in genetically predisposed individuals. The underl...

  • Article
  • Open Access
9 Citations
5,517 Views
11 Pages

TG6 Auto-Antibodies in Dermatitis Herpetiformis

  • Marios Hadjivassiliou,
  • Timo Reunala,
  • Kaisa Hervonen,
  • Pascale Aeschlimann and
  • Daniel Aeschlimann

21 September 2020

Dermatitis herpetiformis (DH) is an extraintestinal manifestation of gluten sensitivity, in which an autoimmune response is directed against transglutaminase 3 (TG3), an epidermal transglutaminase. TG2 is the autoantigen in celiac disease (CD), defin...

  • Case Report
  • Open Access
11 Citations
11,311 Views
8 Pages

Celiac Disease Presenting with Peripheral Neuropathy in Children: A Case Report

  • Alessandra Pacitto,
  • Alessandra Paglino,
  • Lorenza Di Genova,
  • Alberto Leonardi,
  • Edoardo Farinelli,
  • Nicola Principi,
  • Giuseppe Di Cara and
  • Susanna Esposito

Background: Clinically relevant neurological manifestations in children with celiac disease (CD) are unusual, especially when they are considered as signs of the onset of the disease. In this paper, a case of Guillain-Barrè syndrome (GBS) as the firs...

  • Review
  • Open Access
13 Citations
11,307 Views
14 Pages

A Comprehensive Review of the Neurological Manifestations of Celiac Disease and Its Treatment

  • Dhir Gala,
  • Shelbie Scharf,
  • Megan Kudlak,
  • Christian Green,
  • Faisal Khowaja,
  • Mili Shah,
  • Vikash Kumar and
  • Gautam Ullal

21 November 2022

Celiac disease (CD) is a common chronic inflammatory disorder occurring in genetically predisposed individuals secondary to gluten ingestion. CD usually presents with gastrointestinal symptoms such as pain, bloating, flatulence, and constipation or d...

  • Review
  • Open Access
39 Citations
13,165 Views
19 Pages

Celiac Disease and Neurological Manifestations: From Gluten to Neuroinflammation

  • Mauro Giuffrè,
  • Silvia Gazzin,
  • Caterina Zoratti,
  • John Paul Llido,
  • Giuseppe Lanza,
  • Claudio Tiribelli and
  • Rita Moretti

8 December 2022

Celiac disease (CD) is a complex multi-organ disease with a high prevalence of extra-intestinal involvement, including neurological and psychiatric manifestations, such as cerebellar ataxia, peripheral neuropathy, epilepsy, headache, cognitive impair...

  • Review
  • Open Access
3 Citations
5,506 Views
15 Pages

Celiac disease (CD), also known as gluten-sensitive enteropathy, is an inflammatory autoimmune reaction triggered by ingestion of gluten in genetically predisposed subjects. Celiac disease is often associated with a wide range of disorders, caused by...

  • Case Report
  • Open Access
3 Citations
798 Views
3 Pages

Enteropathy-Associated T Cell Lymphoma as a Complication of Silent Celiac Disease

  • Margarida Dantas Brito,
  • Ângelo Martins,
  • Rui Henrique and
  • José Mariz

9 December 2014

Celiac disease is an autoimmune disorder in which a genetic predisposition and the ingestion of wheat gluten triggers a deleterious immune response. This response is complex and may lead to manifestations other than enteropathyha: hepatitis, dermatit...