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7 Results Found

  • Article
  • Open Access
7 Citations
4,297 Views
14 Pages

Analyses and Correlation of Pathologic and Ocular Cutaneous Changes in Murine Graft versus Host Disease

  • Robert B. Levy,
  • Hazem M. Mousa,
  • Casey O. Lightbourn,
  • Eric J. Shiuey,
  • David Latoni,
  • Stephanie Duffort,
  • Ryan Flynn,
  • Jing Du,
  • Henry Barreras and
  • Victor L. Perez
  • + 3 authors

24 December 2021

Graft versus host disease (GVHD) is initiated by donor allo-reactive T cells activated against recipient antigens. Chronic GVHD (cGVHD) is characterized by immune responses that may resemble autoimmune features present in the scleroderma and Sjogren&...

  • Case Report
  • Open Access
1,703 Views
11 Pages

Biopsy-Proven Solid Organ Transplant Graft-Versus-Host Disease (SOT-GVHD) Involving the Skin, Liver, and Bone Marrow in a Simultaneous Kidney-Pancreas Transplant Recipient

  • Reza Rahimi Shahmirzadi,
  • Danielle Ouellette,
  • Martin Igbokwe,
  • Alp Sener,
  • Manal Y. Gabril,
  • Subrata Chakrabarti,
  • Uday Deotare and
  • Lili Ataie

Background: Graft-versus-host disease (GVHD) is a rare but serious complication following solid organ transplantation (SOT), particularly in transplants involving organs with a high volume of passenger donor T-lymphocytes. This case highlights the cl...

  • Case Report
  • Open Access
1 Citations
4,152 Views
6 Pages

19 January 2023

Kaposi sarcoma is relatively common after solid organ transplantation, but very rare after hematopoietic stem cell transplant (HSCT). Here we are reporting a rare case of Kaposi sarcoma in a child after HSCT. An 11-year-old boy with Fanconi anemia wa...

  • Review
  • Open Access
4 Citations
3,150 Views
13 Pages

7 February 2025

Chronic graft-versus-host disease (GVHD) occurs in 30–70% of patients after allogeneic hematopoietic cell transplantation (HCT) and increases the risks of morbidity and mortality. Systemic corticosteroids are the standard initial treatment, but...

  • Perspective
  • Open Access
58 Citations
15,214 Views
14 Pages

17 June 2020

The human skin hosts innumerable microorganisms and maintains homeostasis with the local immune system despite the challenges offered by environmental factors such as ultraviolet radiation (UVR). UVR causes cutaneous alterations such as acute (i.e.,...

  • Article
  • Open Access
5 Citations
2,715 Views
14 Pages

Umbilical Cord Blood Platelet Lysate Eyedrops for the Treatment of Severe Ocular Surface Disorders in Graft vs. Host Disease Patients: Clinical Study

  • Caterina Gagliano,
  • Roberta Foti,
  • Marco Zeppieri,
  • Antonino Maniaci,
  • Salvatore Lavalle,
  • Giuseppa Tancredi,
  • Giuseppe Gagliano,
  • Alessandro Avitabile,
  • Ludovica Cannizzaro and
  • Rosario Foti

5 October 2024

Background: Graft-versus-host disease (GvHD) is an overactive systemic inflammatory response that can arise following allogeneic hematopoietic stem cell transplantation (HSCT). This condition occurs when the transplanted donor immune cells recognize...

  • Case Report
  • Open Access
2 Citations
6,335 Views
9 Pages

A 19-year-old female with a history of pre-B cell acute lymphocytic leukemia (ALL) presented with two aggressive cutaneous squamous cell carcinomas (C-SCC) in the right hand. The patient was diagnosed with pre-B cell ALL at four years of age. She und...