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8 Results Found

  • Article
  • Open Access
2 Citations
4,285 Views
13 Pages
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Laboratory Rat Thrombi Lose One-Third of Their Stiffness When Exposed to Large Oscillating Shear Stress Amplitudes: Contrasting Behavior to Human Clots

  • Ursula Windberger,
  • Veronika Glanz and
  • Leon Ploszczanski
Int. J. Transl. Med.2022, 2(3), 332-344;https://doi.org/10.3390/ijtm2030026

12 July 2022

Rats impress by their high platelet count resulting in hypercoagulability, which protects the animals from severe bleeding. However, platelets also import numerous stiff junction points into the fibrous system of a clot, also enhancing the pre-stress...

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  • Article
  • Open Access
1,131 Views
17 Pages
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Numerical Simulation of Blood Clot Extraction Process Using Aspiration-Based Mechanical Thrombectomy

  • Sreenivas Venguru,
  • Shyam Sunder Yadav,
  • Tanmaya Mahapatra and
  • Sanjay Kumar Kochar
Fluids2025, 10(5), 124;https://doi.org/10.3390/fluids10050124

9 May 2025

This paper simulates the blood clot extraction process inside an idealized cylindrical blood vessel model using the aspiration-based thrombectomy technique. A fully Eulerian technique is used within the finite volume method where incompressible Navie...

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  • Article
  • Open Access
209 Views
21 Pages
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Neutrophil Extracellular Traps Promote Platelet-Driven Contraction of Inflammatory Blood Clots via Local Generation of Endogenous Thrombin and Softening of the Fibrin Network

  • Shakhnoza M. Saliakhutdinova,
  • Rafael R. Khismatullin,
  • Alina I. Khabirova,
  • Rustem I. Litvinov and
  • John W. Weisel
Cells2025, 14(24), 2018;https://doi.org/10.3390/cells14242018

18 December 2025

Immunothrombosis can substantially affect the course and outcomes of severe infections and immune-mediated diseases. While inflammatory thrombi are neutrophil-rich, impact of neutrophils on clot contraction, a key modulator of thrombus stability and...

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  • Article
  • Open Access
9 Citations
3,959 Views
19 Pages
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Blood Clot Phenotyping by Rheometry: Platelets and Fibrinogen Chemistry Affect Stress-Softening and -Stiffening at Large Oscillation Amplitude

  • Ursula Windberger and
  • Jörg Läuger
Molecules2020, 25(17), 3890;https://doi.org/10.3390/molecules25173890

26 August 2020

(1) Background: Together with treatment protocols, viscoelastic tests are widely used for patient care. Measuring at broader ranges of deformation than currently done will add information on a clot’s mechanical phenotype because fibrin networks follo...

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  • Article
  • Open Access
2 Citations
1,807 Views
23 Pages
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Three-Dimensional Modeling of the Behavior of a Blood Clot Using Different Mechanical Properties of a Blood Vessel

  • Mantas Brusokas,
  • Sergejus Borodinas and
  • Raimondas Jasevičius
Mathematics2025, 13(2), 285;https://doi.org/10.3390/math13020285

17 January 2025

In this work, the behavior of a 3D blood clot located inside a vein under the influence of the mechanical effect of blood flow was analyzed. It has been observed that the mechanical properties of the blood vessel play an important role in the behavio...

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  • Open Access
2 Citations
3,005 Views
16 Pages
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Numerical Analysis of Blood Clot Mechanical Behavior in Relation to Blood Flow Inside the Popliteal Vein

  • Mantas Brusokas and
  • Raimondas Jasevičius
Mathematics2024, 12(2), 267;https://doi.org/10.3390/math12020267

14 January 2024

In this work, blood clot behavior under the influence of the mechanical effect of blood flow was analyzed. Attention is mainly paid to the deformation of the thrombus in the event of an alternating effect of blood flow in the blood vessel of the huma...

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  • Open Access
6 Citations
2,483 Views
14 Pages
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Effects of a Maximal Exercise Followed by a Submaximal Exercise Performed in Normobaric Hypoxia (2500 m), on Blood Rheology, Red Blood Cell Senescence, and Coagulation in Well-Trained Cyclists

  • Romain Carin,
  • Gabriel Deglicourt,
  • Hamdi Rezigue,
  • Marie Martin,
  • Christophe Nougier,
  • Camille Boisson,
  • Yesim Dargaud,
  • Philippe Joly,
  • Céline Renoux and
  • Philippe Connes
  • + 2 authors
Metabolites2023, 13(2), 179;https://doi.org/10.3390/metabo13020179

25 January 2023

Acute normoxic exercise impacts the rheological properties of red blood cells (RBC) and their senescence state; however, there is a lack of data on the effects of exercise performed in hypoxia on RBC properties. This crossover study compared the effe...

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  • Article
  • Open Access
12 Citations
3,460 Views
10 Pages
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Inversion of Left Atrial Appendage Will Cause Compressive Stresses in the Tissue: Simulation Study of Potential Therapy

  • Salvatore Pasta,
  • Julius M. Guccione and
  • Ghassan S. Kassab
J. Pers. Med.2022, 12(6), 883;https://doi.org/10.3390/jpm12060883

27 May 2022

In atrial fibrillation (AF), thromboembolic events can result from the particular conformation of the left atrial appendage (LAA) bearing increased clot formation and accumulation. Current therapies to reduce the risk of adverse events rely on surgic...

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