Cardiac resynchronisation therapy may lead to remarkable improvement in clinical status in selected patients with heart failure. However, approximately 20% of patients may not respond to this treatment. A major challenge lies in reducing the number o...
Introduction: The efficacy of de novo cardiac resynchronisation therapy (CRT) in patients with heart failure (HF), left ventricular systolic dysfunction (LVSD), and a broad QRS morphology is well established. However, the optimal stage for upgrading...
Introduction: Cardiac resynchronisation therapy is ineffective in 30–40% of patients with heart failure with reduced ejection fraction. Targeting non-scarred myocardium by selecting the site of latest mechanical activation using echocardiograph...
Cardiac resynchronisation therapy (CRT) has become the cornerstone of heart failure (HF) treatment. Despite the obvious benefit from this therapy, an estimated 30% of CRT patients do not respond (“non-responders”). The cause of “non...
Background: According to current guidelines, cardiac resynchronisation therapy (CRT) is recommended in patients with significantly impaired left ventricular systolic function and left bundle branch block. However, the decision between pacemaker (CRT-...
Echocardiogaphy in cardiac resynchronisation therapy. An uncoordinated contraction process in patients with cardiac failure is a contributory factor in restricting haemodynamic function independently of myocardial damage at cell level. Cardiac resync...
19 March 2014
Cardiac resynchronisation therapy with multisite left ventricular stimulation. Up to 30% of patients do not respond to conventional cardiac resynchronisation therapy (CRT). The recently introduced multisite pacing was developed to reduce this number....
Over the past few years, the field of cardiac stimulation has witnessed the accelerated development of leadless cardiac pacing, a technology first conceived almost 50 years ago. Currently, two fully intracardiac devices allow single-chamber right-ven...
While substantial progress has been made over the past decade in the medical treatment of heart failure, certain patients fail to respond to optimal treatment despite the availability of excellent drugs. Cardiac resynchronisation therapy, or multisit...
The first artificial pacemaker was implanted 51 years ago. Considerable progress has been made in recent decades and pacemakers have become fully automated cardiac rhythm management (CRM) systems representing a new, growing, and important set of ther...
The authors report on a patient with ischaemic cardiopathy and chronic congestive heart failure treated with a cardiac resynchronisation therapy device with a defibrillator back-up (CRT-D), who experienced two syncopal episodes. The first syncope was...
Background/Objectives: Whether remote monitoring reduces mortality in patients with heart failure remains controversial, and research on remote monitoring in South Korea is generally lacking. Therefore, we aim to evaluate the safety and efficacy of r...
Background: Diagnosis of ventricular dyssynchrony may play a role in patient selection for cardiac resynchronisation therapy. Various imaging techniques are available for diagnosis of dyssynchrony, including echocardiography and radionuclide imaging....
Backround: “Ablate-and-pace” is an established procedure for selected patients with drug-refractory atrial fibrillation (AF). As consecutive right-ventricular pacing might have deleterious effects on left ventricular ejection fraction (LVEF), cardiac...
Direct His bundle pacing has recently attracted interest as a more physiological alternative to right ventricular or biventricular stimulation. The advent of new tools has facilitated the implantation procedure. This report relates our initial experi...
Guidelines for remote monitoring of implanted devices for diagnosis and treatment of arrhythmias and heart failure. Implanted devices for diagnosis and treatment of arrhythmias and heart failure comprise event recorders, pacemakers, automatic defibri...
Implanted devices for diagnosis and treatment of arrhythmias and heart failure comprise event recorders, pacemakers, automatic defibrillators (ICD) and biventricular stimulating devices for the treatment of severe heart failure (cardiac resynchronisa...
Cardiac resynchronisation therapy (CRT) using biventricular pacing has become standard of care for patients with symptomatic heart failure, wide QRS and left ventricular ejection fraction (LVEF) <35% refractory to optimal medical treatment. Convin...
The subcutaneous ICD (S-ICD) has recently been introduced as an alternative to transvenous devices. The system preserves venous access and reduces risk of lead issues and of systemic infection. However, pacing for antitachycardia, antibradycardia and...
Background: Echocardiography-based programming of conduction delays in cardiac resynchronisation therapy is complex and time-consuming. Impedance cardiography (ICG) may be an alternative method. However, it is unknown whether ICG is sensitive enough...
In the light of possible restrictions to the number of pacemaker implantations in Switzerland and missing local data on this topic, we aimed to evaluate if the pacemaker indications in a tertiary Swiss hospital are in accordance with current guidelin...
Important advances have been made in the past few years in the fields of clinical cardiac electrophysiology and pacing. Researchers and clinicians have a greater understanding of the pathophysiological mechanisms underlying atrial fibrillation (AF),...
The 2015 European Society of Cardiology guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death (SCD) is a European update of the joint guidelines with American College of Cardiology/American...
Cardiac implantable electronic devices (CIEDs) such as pacemakers, implantable cardioverter-defibrillators (ICDs), and cardiac resynchronisation therapy (CRT) devices are generating unprecedented volumes of data in both inpatient and remote settings....
(1) Background: Cardiac resynchronisation therapy (CRT) is nowadays an indispensable treatment option for heart failure. Although the indication is subject to clear cross-national guidelines by the European Society of Cardiology (ESC), there is immen...
Coronary artery disease (CAD) is in large part responsible for cardiovascular morbidity and mortality in the Western world. Therefore diagnostic tools for the assessment of CAD, such as cardiovascular magnetic resonance (CMR) imaging, have become inc...
The incidence of heart failure is increasing and patients are threatened to die of pump failure as well as of sudden cardiac death (SCD). Lately, cardiac resynchronisation therapy (CRT) has been introduced to treat patients with persistent heart fail...
In patients with end-stage heart failure refractory to medical and cardiac resynchronisation therapy, heart transplantation is recognised as the treatment of choice. As compared to medical therapy, heart transplantation is considered to be associated...
Background: Cardiac resynchronisation therapy (CRT) has become a mainstay in the treatment of patients with severe heart failure mainly due to large clinical trials demonstrating a reduction in morbidity and mortality. The aim of the present study wa...
Ischaemic mitral regurgitation (IMR) is defined as functional MR with systolic restriction of leaflet motion, apical and lateral displacement of the subvalvular apparatus, and annular dilatation in the presence of a morphologically normal mitral valv...