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13 Results Found

  • Article
  • Open Access
1,320 Views
10 Pages

Association of SGLT2 Inhibitors with Mortality and Bioprosthesis Valve Failure After TAVR: A Propensity-Matched Cohort Study

  • Olivier Morel,
  • Amandine Granier,
  • Lisa Lochon,
  • Antonin Trimaille,
  • Arnaud Bisson,
  • Benjamin Marchandot,
  • Anne Bernard and
  • Laurent Fauchier

3 October 2025

Background: Sodium–glucose cotransporter 2 inhibitors (SGLT2i) have shown cardioprotective effects beyond glucose control. In aortic stenosis, SGLT2 expression is upregulated in myocardium and valve tissue, contributing to inflammation, oxidati...

  • Article
  • Open Access
968 Views
12 Pages

Redo-Transcatheter Aortic Valve Implantation (Redo-TAVI)—Pilot Study from Multicentre Nationwide Registry

  • Szymon Jonik,
  • Maciej Mazurek,
  • Bartosz Rymuza,
  • Jan Jankowski,
  • Maciej Dąbrowski,
  • Rafał Wolny,
  • Piotr Chodór,
  • Krzysztof Wilczek,
  • Wojciech Fil and
  • Zenon Huczek
  • + 12 authors

14 November 2025

Objectives: The aim of this study is to evaluate the safety and efficacy of repeat transcatheter aortic valve implantation (redo-TAVI) in the polish population. Methods: In this multicentre nationwide registry (ClinicalTrials.gov identifier, NCT03361...

  • Review
  • Open Access
14 Citations
3,759 Views
21 Pages

Early Biological Valve Failure: Structural Valve Degeneration, Thrombosis, or Endocarditis?

  • Fabio Fazzari,
  • Andrea Baggiano,
  • Laura Fusini,
  • Sarah Ghulam Ali,
  • Paola Gripari,
  • Daniele Junod,
  • Maria Elisabetta Mancini,
  • Riccardo Maragna,
  • Saima Mushtaq and
  • Manuela Muratori
  • + 2 authors

3 September 2023

Biological valve failure (BVF) is an inevitable condition that compromises the durability of biological heart valves (BHVs). It stems from various causes, including rejection, thrombosis, and endocarditis, leading to a critical state of valve dysfunc...

  • Article
  • Open Access
199 Views
12 Pages

Reintervention for Failed Aortic Bioprostheses: Distinct Patient Profiles for Redo Surgery and Valve-in-Valve TAVR in an All-Comers Cohort

  • Daniela Geisler,
  • Zsuzsanna Arnold,
  • Marieluise Harrer,
  • Rudolf Seemann,
  • Georg Delle-Karth,
  • Martin Grabenwöger and
  • Markus Mach

7 January 2026

Background/Objectives: Aortic valve therapy increasingly follows a lifetime management concept. As all bioprostheses ultimately degenerate, optimal outcomes rely on the appropriate selection and timing of treatment modality. This study evaluates outc...

  • Article
  • Open Access
3 Citations
1,721 Views
9 Pages

Conventional vs. Sutureless Aortic Valve Bioprosthesis: Is Faster Better?

  • Ali Aljalloud,
  • Ajay Moza,
  • Jessica Paola Arias,
  • Matthias Menne,
  • Michael Becker and
  • Konstantina Spetsotaki

Purpose: The benefits of sutureless compared to conventional aortic valve prosthesis replacement remain controversial. Supposed advantages of sutureless aortic valve replacement include shortened cross-clamp and implantation time, as well as improved...

  • Review
  • Open Access
8 Citations
3,251 Views
10 Pages

Transcatheter Aortic Valve Implantation in Younger Patients: A New Challenge

  • Giacomo Virgili,
  • Salvatore Mario Romano,
  • Renato Valenti,
  • Angela Migliorini,
  • Pierluigi Stefàno,
  • Niccolò Marchionni and
  • Nazario Carrabba

27 August 2021

The number of aortic stenosis patients in Western countries is increasing, along with better life conditions and expectancies. Presently, the volume of percutaneous transcatheter aortic valve implantations (TAVIs) is incessantly increasing, and has a...

  • Review
  • Open Access
10 Citations
3,949 Views
16 Pages

13 November 2023

This review explores the use of bioprosthetic valves for the lifetime management of patients with aortic stenosis, considering recent advancements in surgical (SAV) and transcatheter bioprostheses (TAV). We examine the strengths and challenges of eac...

  • Review
  • Open Access
18 Citations
3,093 Views
9 Pages

Use of Sutureless and Rapid Deployment Prostheses in Challenging Reoperations

  • Igor Vendramin,
  • Andrea Lechiancole,
  • Daniela Piani,
  • Gaetano Nucifora,
  • Giovanni Benedetti,
  • Sandro Sponga,
  • Daniele Muser,
  • Uberto Bortolotti and
  • Ugolino Livi

Sutureless and rapid-deployment bioprostheses have been introduced as alternatives to traditional prosthetic valves to reduce cardiopulmonary and aortic cross-clamp times during aortic valve replacement. These devices have also been employed in extre...

  • Article
  • Open Access
371 Views
7 Pages

Early Degeneration of the Sorin Mitroflow Aortic Bioprosthesis

  • Fritz Widmer,
  • Florian Schliephake,
  • Daniel Mattle and
  • Martin Federmann

We report a series of 31 patients after surgical aortic valve implantation of a bovine Sorin Mitroflow bioprosthesis with early severe structural valve degeneration (SVD) despite absence of known risk factors. Half of the patients underwent re-interve...

  • Article
  • Open Access
3 Citations
2,685 Views
13 Pages

Hedinger Syndrome—Lessons Learnt: A Single-Center Experience

  • Mohamed El Gabry,
  • Sven Arends,
  • Sharaf-Eldin Shehada,
  • Harald Lahner,
  • Markus Kamler,
  • Daniel Wendt and
  • Konstantina Spetsotaki

Background: Hedinger syndrome (HS) or carcinoid heart disease (CD) is a rare and challenging manifestation of malignant neuroendocrine tumours (NETs) involving the heart. We aimed to report our experience with surgical strategies and midterm results...

  • Case Report
  • Open Access
1 Citations
3,669 Views
11 Pages

An Aminoglycoside-Sparing Regimen with Double Beta-Lactam to Successfully Treat Granulicatella adiacens Prosthetic Aortic Valve Endocarditis—Time to Change Paradigm?

  • Alberto Pagotto,
  • Floriana Campanile,
  • Paola Conti,
  • Francesca Prataviera,
  • Paola Della Siega,
  • Sarah Flammini,
  • Simone Giuliano,
  • Luca Martini,
  • Davide Pecori and
  • Carlo Tascini
  • + 3 authors

14 March 2024

(1) Background: Granulicatella adiacens is a former nutritionally variant streptococci (NVS). NVS infective endocarditis (IE) is generally characterized by a higher rate of morbidity and mortality, partially due to difficulties in choosing the most a...

  • Article
  • Open Access
995 Views
14 Pages

Snorkel Stenting During Transcatheter Aortic Valve Implantation: A Single-Center Study

  • Massimo Baudo,
  • Serge Sicouri,
  • Yoshiyuki Yamashita,
  • Dimitrios E. Magouliotis,
  • Francesco Cabrucci,
  • Sarah M. Carnila,
  • Scott M. Goldman,
  • Eric M. Gnall,
  • William A. Gray and
  • Basel Ramlawi
  • + 1 author

16 September 2025

Background and Objectives: Coronary obstruction (CO) is a potentially fatal complication that can occur during transcatheter aortic valve implantation (TAVI). The snorkel stenting technique was developed to mitigate the risk of CO. The aim of the cur...

  • Article
  • Open Access
1 Citations
1,201 Views
6 Pages

Aortic root surgery: Early postoperative results of different surgical techniques

  • Rimantas Benetis,
  • Eglė Ereminienė,
  • Povilas Jakuška,
  • Dainius Karčiauskas,
  • Šarūnas Kinduris,
  • Algimantas Budrikis,
  • Adakrius Siudikas,
  • Jolanta Justina Vaškelytė,
  • Algimantas Sasnauskas and
  • Kastytis Vaičiulis
  • + 1 author

10 March 2009

The aim of the study was to evaluate early postoperative results of different surgical techniques of aortic root surgery. Material and methods. Between January 2004 and November 2007, a cohort of 83 patients underwent aortic root surgery in the Hear...