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Article

3 Citations

2,499 Views

21 Pages

Effect of Linear Energy Transfer on Cystamine’s Radioprotective Activity: A Study Using the Fricke Dosimeter with 6–500 MeV per Nucleon Carbon Ions—Implication for Carbon Ion Hadrontherapy

Samafou Penabeï,
Esteban Sepulveda,
Abdullah Muhammad Zakaria,
Jintana Meesungnoen and
Jean-Paul Jay-Gerin

Molecules2023, 28(24), 8144;https://doi.org/10.3390/molecules28248144

18 December 2023

(1) Background: Radioprotective agents have garnered considerable interest due to their prospective applications in radiotherapy, public health medicine, and situations of large-scale accidental radiation exposure or impending radiological emergencie...

(This article belongs to the Section Medicinal Chemistry)

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Article

6 Citations

2,930 Views

23 Pages

Comparative Analysis of Cystamine and Cysteamine as Radioprotectors and Antioxidants: Insights from Monte Carlo Chemical Modeling under High Linear Energy Transfer Radiation and High Dose Rates

Samafou Penabeï,
Jintana Meesungnoen and
Jean-Paul Jay-Gerin

Int. J. Mol. Sci.2024, 25(19), 10490;https://doi.org/10.3390/ijms251910490

29 September 2024

This study conducts a comparative analysis of cystamine (RSSR), a disulfide, and cysteamine (RSH), its thiol monomer, to evaluate their efficacy as radioprotectors and antioxidants under high linear energy transfer (LET) and high-dose-rate irradiatio...

(This article belongs to the Section Physical Chemistry and Chemical Physics)

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