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18 Results Found

  • Article
  • Open Access
81 Citations
19,594 Views
12 Pages

15 October 2008

Phenolcarboxylic acid antioxidants do not act in vivo as radical-scavengers in isolation, but rather together with GSH (glutathione), a coantioxidant, they constitute an intricate antioxidant network. Caffeic acid, p-coumaric acid, ferulic acid and c...

  • Article
  • Open Access
2 Citations
1,665 Views
16 Pages

Comparative Analyses of Biologically Active Substances and Antioxidant Activity in Fresh and Stored Fruits of Apple Varieties from the Republic of Tajikistan

  • Vera A. Kostikova,
  • Mariyo T. Boboev,
  • Mathew T. Sharples,
  • Amonullo K. Namozov,
  • Saimuhammad B. Yoqubov,
  • Jovidon T. Boboev,
  • Shukherdorj Baasanmunkh,
  • Hyeok Jae Choi,
  • Alexander A. Kuznetsov and
  • Andrey S. Erst
  • + 3 authors

11 November 2024

Our purpose was to carry out a comparative phytochemical analysis of fruits (both fresh and stored for 1 month) of two local apple varieties of the Republic of Tajikistan. Assays were carried out to quantify total phenolic compounds, flavonols, catec...

  • Article
  • Open Access
3 Citations
2,164 Views
14 Pages

Study on Quality Characteristic of Chebulae Fructus and Its Adulterants and Degradation Pathway of Hydrolyzable Tannins

  • Jian Xu,
  • Xiangdong Wang,
  • Huijuan Yu,
  • Xin Chai,
  • Min Zhang,
  • Hong-Hua Wu and
  • Yuefei Wang

Chebulae Fructus (CF) is known as one of the richest sources of hydrolyzable tannins (HTs). In this study, ultra-performance liquid chromatography coupled with a photodiode array detector method was established for simultaneous determination of the 1...

  • Article
  • Open Access
5 Citations
1,615 Views
13 Pages

17 August 2023

Plants in high-altitude habitats are exposed to severe environmental stressors, including extreme temperatures and irradiation, which can have wide-ranging effects on changes of secondary-metabolite profiles in higher plants. Altitude-related variati...

  • Article
  • Open Access
3 Citations
3,054 Views
11 Pages

16 February 2023

Sorbaria pallasii is an endemic species of the Far East and Siberia and grows along the Goltsy altitudinal belt. Data on micropropagation and phytochemical characteristics of this plant are not available, probably because of the inaccessibility of th...

  • Article
  • Open Access
4 Citations
2,413 Views
18 Pages

Chemical Composition of Methanol Extracts from Leaves and Flowers of Anemonopsis macrophylla (Ranunculaceae)

  • Vera A. Kostikova,
  • Natalia V. Petrova,
  • Alexander A. Chernonosov,
  • Vladimir V. Koval,
  • Evgeniia R. Kovaleva,
  • Wei Wang and
  • Andrey S. Erst

Anemonopsis Siebold et Zucc. is an unstudied single-species genus belonging to the tribe Cimicifugeae (Ranunculaceae). The only species of this genus—Anemonopsis macrophylla Siebold and Zucc.—is endemic to Japan. There are no data on its...

  • Article
  • Open Access
31 Citations
5,036 Views
15 Pages

13 August 2018

Phenolic acids and its methoxy derivatives are known to induce caspase-mediated apoptosis activity and exhibit cytotoxic effect towards various cancer cell lines. However, their low stability and poor bioavailability in the human organism extensively...

  • Article
  • Open Access
7 Citations
2,685 Views
15 Pages

Non-Targeted Screening of Metabolites in Aqueous-Ethanol Extract from Spiraea hypericifolia (Rosaceae) Using LC-HRMS

  • Vera A. Kostikova,
  • Natalia V. Petrova,
  • Tatiana M. Shaldaeva,
  • Vladimir V. Koval and
  • Alexander A. Chernonosov

8 September 2023

By means of liquid chromatography combined with high-resolution mass spectrometry, metabolite profiling was performed on an aqueous-ethanol extract from Spiraea hypericifolia (Rosaceae) collected in Siberia (Russia). Up to 140 compounds were found in...

  • Article
  • Open Access
86 Citations
10,937 Views
17 Pages

Ultrasound-Assisted Extraction of Carnosic Acid and Rosmarinic Acid Using Ionic Liquid Solution from Rosmarinus officinalis

  • Ge Zu,
  • Rongrui Zhang,
  • Lei Yang,
  • Chunhui Ma,
  • Yuangang Zu,
  • Wenjie Wang and
  • Chunjian Zhao

5 September 2012

Ionic liquid based, ultrasound-assisted extraction was successfully applied to the extraction of phenolcarboxylic acids, carnosic acid and rosmarinic acid, from Rosmarinus officinalis. Eight ionic liquids, with different cations and anions, were inve...

  • Article
  • Open Access
7 Citations
2,612 Views
25 Pages

8 December 2023

An integrative strategy of UHPLC/IM-QTOF-MS analysis, MS/MS molecular networking (MN), in-house library search, and a collision cross-section (CCS) simulation and comparison was developed for the rapid characterization of the chemical constituents in...

  • Review
  • Open Access
27 Citations
6,970 Views
36 Pages

16 October 2021

The genus Spiraea L. belongs to the Rosaceae Juss. family and includes more than 100 species distributed in the temperate zone and subtropical zone of the Northern Hemisphere at the center of species diversity in East Asia. Representatives of the gen...

  • Article
  • Open Access
44 Citations
10,014 Views
19 Pages

3 December 2018

p-Coumaric acid is a commercially available phenolcarboxylic acid with a great number of important applications in the nutraceutical, pharmaceutical, material and chemical industries. p-Coumaric acid has been biosynthesized in some engineered microbe...

  • Article
  • Open Access
11 Citations
8,325 Views
31 Pages

Phytochemical Characterization and Antioxidant Activity Evaluation for Some Plant Extracts in Conjunction with Pharmacological Mechanism Prediction: Insights into Potential Therapeutic Applications in Dyslipidemia and Obesity

  • Elena Iuliana Ilie,
  • Liliana Popescu,
  • Emanuela-Alice Luță,
  • Andrei Biță,
  • Alexandru Radu Corbu,
  • Dragoș Paul Mihai,
  • Ana Corina Pogan,
  • Teodora Dalila Balaci,
  • Alexandru Mincă and
  • Cerasela Elena Gîrd
  • + 2 authors

Lipid metabolism dysregulation can lead to dyslipidemia and obesity, which are major causes of cardiovascular disease and associated mortality worldwide. The purpose of the study was to obtain and characterize six plant extracts (ACE—Allii cepa...

  • Article
  • Open Access
14 Citations
3,707 Views
21 Pages

Chemical Composition and Biological Activity of Argentinian Propolis of Four Species of Stingless Bees

  • Valery A. Isidorov,
  • Jolanta Maslowiecka,
  • Lukasz Szoka,
  • Naldo Pellizzer,
  • Dora Miranda,
  • Ewa Olchowik-Grabarek,
  • Monika Zambrzycka and
  • Izabela Swiecicka

9 November 2022

The chemical composition of propolis of four species of stingless bees (SLBs) from Argentina was determined, and its antibacterial and anticancer activity was evaluated on selected types of microbes and cancer cell lines. Volatile secretions of all p...

  • Article
  • Open Access
10 Citations
3,550 Views
31 Pages

Outlook on Chronic Venous Disease Treatment: Phytochemical Screening, In Vitro Antioxidant Activity and In Silico Studies for Three Vegetal Extracts

  • Andreea Roxana Ungureanu,
  • Carmen Lidia Chițescu,
  • Emanuela Alice Luță,
  • Alina Moroșan,
  • Dan Eduard Mihaiescu,
  • Dragoș Paul Mihai,
  • Liliana Costea,
  • Emma Adriana Ozon,
  • Ancuța Cătălina Fița and
  • Cerasela Elena Gîrd
  • + 1 author

23 April 2023

Chronic venous disease is one of the most common vascular diseases; the signs and symptoms are varied and are often neglected in the early stages. Vascular damage is based on proinflammatory, prothrombotic, prooxidant activity and increased expressio...

  • Review
  • Open Access
75 Citations
9,914 Views
52 Pages

Alleviation of Multidrug Resistance by Flavonoid and Non-Flavonoid Compounds in Breast, Lung, Colorectal and Prostate Cancer

  • Teodora Costea,
  • Oana Cezara Vlad,
  • Luminita-Claudia Miclea,
  • Constanta Ganea,
  • János Szöllősi and
  • Maria-Magdalena Mocanu

The aim of the manuscript is to discuss the influence of plant polyphenols in overcoming multidrug resistance in four types of solid cancers (breast, colorectal, lung and prostate cancer). Effective treatment requires the use of multiple toxic chemot...

  • Article
  • Open Access
15 Citations
4,938 Views
25 Pages

Echinacea purpurea Fractions Represent Promising Plant-Based Anti-Inflammatory Formulations

  • Sara F. Vieira,
  • Samuel M. Gonçalves,
  • Virgínia M. F. Gonçalves,
  • Carmen P. Llaguno,
  • Felipe Macías,
  • Maria Elizabeth Tiritan,
  • Cristina Cunha,
  • Agostinho Carvalho,
  • Rui L. Reis and
  • Nuno M. Neves

9 February 2023

Echinacea purpurea is traditionally used in the treatment of inflammatory diseases. Therefore, we investigated the anti-inflammatory capacity of E. purpurea dichloromethanolic (DE) and ethanolic extracts obtained from flowers and roots (R). To identi...

  • Review
  • Open Access
91 Citations
17,482 Views
21 Pages

Caffeine and Its Antioxidant Properties—It Is All about Dose and Source

  • Bianca-Eugenia Ősz,
  • George Jîtcă,
  • Ruxandra-Emilia Ștefănescu,
  • Amalia Pușcaș,
  • Amelia Tero-Vescan and
  • Camil-Eugen Vari

28 October 2022

Caffeine is the most frequently used substance with a central nervous system stimulant effect, but its consumption is most often due to the intake of foods and drinks that contain it (coffee, tea, chocolate, food supplements with plant extracts of Gu...