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4 Results Found

  • Feature Paper
  • Article
  • Open Access
13 Citations
3,755 Views
17 Pages

Comparable Response Following Exposure to Biodiesel and Diesel Exhaust Particles in Advanced Multicellular Human Lung Models

  • Mizanur Rahman,
  • Swapna Upadhyay,
  • Koustav Ganguly,
  • Micol Introna,
  • Jie Ji,
  • Christoffer Boman,
  • Ala Muala,
  • Anders Blomberg,
  • Thomas Sandström and
  • Lena Palmberg

14 June 2023

Biodiesel is considered to be a sustainable alternative for fossil fuels such as petroleum-based diesel. However, we still lack knowledge about the impact of biodiesel emissions on humans, as airways and lungs are the primary target organs of inhaled...

(This article belongs to the Section Air Pollution and Health)
  • Article
  • Open Access
22 Citations
4,547 Views
23 Pages

Cigarette Smoke Impairs Airway Epithelial Wound Repair: Role of Modulation of Epithelial-Mesenchymal Transition Processes and Notch-1 Signaling

  • Serena Di Vincenzo,
  • Dennis K. Ninaber,
  • Chiara Cipollina,
  • Maria Ferraro,
  • Pieter S. Hiemstra and
  • Elisabetta Pace

12 October 2022

Cigarette smoke (CS) induces oxidative stress and chronic inflammation in airway epithelium. It is a major risk factor for respiratory diseases, characterized by epithelial injury. The impact of CS on airway epithelial repair, which involves epitheli...

(This article belongs to the Special Issue Airway Inflammation Induced by Oxidative Stress)
  • Article
  • Open Access
10 Citations
4,817 Views
19 Pages

Analysis of Nipah Virus Replication and Host Proteome Response Patterns in Differentiated Porcine Airway Epithelial Cells Cultured at the Air–Liquid Interface

  • Martin Müller,
  • Kerstin Fischer,
  • Elisabeth Woehnke,
  • Luca M. Zaeck,
  • Christoph Prönnecke,
  • Michael R. Knittler,
  • Axel Karger,
  • Sandra Diederich and
  • Stefan Finke

13 April 2023

Respiratory tract epithelium infection plays a primary role in Nipah virus (NiV) pathogenesis and transmission. Knowledge about infection dynamics and host responses to NiV infection in respiratory tract epithelia is scarce. Studies in non-differenti...

(This article belongs to the Section Animal Viruses)
  • Article
  • Open Access
285 Views
16 Pages

Assessment of CFTR Dysfunction and Responsiveness to CFTR Modulators in COPD Bronchial Air–Liquid Interface Cultures

  • Nikhil T. Awatade,
  • Kurtis F. Budden,
  • Prabuddha S. Pathinayake,
  • Andrew T. Reid,
  • Kristy S. Nichol and
  • Peter A. B. Wark

1 October 2026

Increasing evidence suggests that acquired dysfunction of the cystic fibrosis transmembrane conductance regulator (CFTR) anion channel occurs as a result of cigarette smoke exposure in chronic obstructive pulmonary disease (COPD). CFTR-targeted thera...

(This article belongs to the Special Issue Molecular Mechanism and Therapy of Respiratory Diseases)