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3 Results Found

  • Article
  • Open Access
16 Citations
3,081 Views
16 Pages

LncRNA BCYRN1 as a Potential Therapeutic Target and Diagnostic Marker in Serum Exosomes in Bladder Cancer

  • Junya Arima,
  • Hirofumi Yoshino,
  • Wataru Fukumoto,
  • Ichiro Kawahara and ,
  • Saeki Saito,
  • Gang Li,
  • Ikumi Fukuda,
  • Sayaka Iizasa,
  • Akihiko Mitsuke and
  • Hideki Enokida
  • + 11 authors+ 6 authors

Bladder cancer (BC) is a common genitourinary malignancy that exhibits silent morbidity and high mortality rates because of a lack of diagnostic markers and limited effective treatments. Here, we evaluated the role of the lncRNA brain cytoplasmic RNA...

(This article belongs to the Section Molecular Biology)
  • Article
  • Open Access
13 Citations
4,255 Views
12 Pages

Regulator of G Protein Signaling 20 Correlates with Long Intergenic Non-Coding RNA (lincRNAs) Harboring Oncogenic Potential and Is Markedly Upregulated in Hepatocellular Carcinoma

  • Yulu Wang,
  • Maria F. Setiawan,
  • Hongde Liu,
  • Tikam Chand Dakal and ,
  • Hongjia Liu,
  • Fangfang Ge,
  • Oliver Rudan,
  • Peng Chen,
  • Chunxia Zhao and
  • Ingo G. H. Schmidt-Wolf
  • + 11 authors+ 6 authors

4 August 2022

Hepatocellular carcinoma (HCC) is at the forefront of the global cancer burden, and biomarkers for HCC are constantly being sought. Interestingly, RGS (Regulators of G protein signaling) proteins, which negatively regulate GPCR signaling, have been a...

  • Article
  • Open Access
21 Citations
4,407 Views
21 Pages

Targeting BC200/miR218-5p Signaling Axis for Overcoming Temozolomide Resistance and Suppressing Glioma Stemness

  • Yu-Kai Su,
  • Jia Wei Lin,
  • Jing-Wen Shih,
  • Hao-Yu Chuang and ,
  • Iat-Hang Fong,
  • Chi-Tai Yeh and
  • Chien-Min Lin
  • + 2 authors+ 0 author

8 August 2020

Background: Glioblastoma (GB) is one of the most common (~30%) and lethal cancers of the central nervous system. Although new therapies are emerging, chemoresistance to treatment is one of the major challenges in cancer treatment. Brain cytoplasmic 2...

(This article belongs to the Special Issue Molecular and Cellular Mechanisms of Cancers: Glioblastoma)