Viral Pneumonia: Recent Advances and Prospects

Dear Colleagues,

Viral pneumonia is a major global health concern and a common cause of acute respiratory failure, with high morbidity and mortality. Respiratory viruses—including influenza viruses, respiratory syncytial virus (RSV), and coronaviruses (such as SARS-CoV-2)—trigger complex immune responses and can lead to severe lung injury, aberrant repair, and long-term sequelae. Post-viral syndromes, exemplified by "long COVID", have further highlighted the urgent need to understand the immunopathology and regenerative dynamics following viral lung infections.

This Special Issue will highlight recent advances in our understanding of viral pneumonia, focusing on the molecular mechanisms behind lung injury, host immune responses, alveolar regeneration, and viral persistence. We welcome original research articles, reviews, and commentaries addressing topics such as innate and adaptive immunity in viral pneumonia, dysregulated inflammation, epithelial and endothelial repair mechanisms, and immune–metabolic interactions. Submissions exploring the long-term consequences of viral infections, including post-viral fibrosis and chronic immune activation, are particularly encouraged.

We also invite studies employing advanced technologies such as single-cell omics, organoid models, and spatial profiling to dissect host–virus interactions and tissue remodeling.

We hope that this Special Issue will foster interdisciplinary dialog and provide novel insights to guide future diagnostics, therapeutics, and preventive strategies.

Prof. Dr. Gan Zhao
Guest Editor

Manuscript Submission Information

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