Molecular Mechanisms and Structural Biology of High-Pathogenicity RNA Viruses
A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "General Virology".
Deadline for manuscript submissions: 31 March 2027 | Viewed by 58
Special Issue Editor
Interests: COVID-19; SARS-CoV-2; lymphoma; cancer research; viral infections; kidney disease; long-term care; chronic myeloid leukemia; myocarditis
Special Issue Information
Dear Colleagues,
High-pathogenicity RNA viruses represent some of the most significant threats to global health, as demonstrated by outbreaks caused by viruses such as SARS-CoV-2, Ebola virus, Marburg virus, Nipah virus, and highly pathogenic strains of influenza A virus. These viruses are characterized by rapid mutation rates, complex host interactions, and sophisticated mechanisms that enable immune evasion, efficient replication, and severe pathogenic outcomes. Understanding the molecular and structural basis of these processes is essential for the development of effective antiviral therapeutics, vaccines, and diagnostic tools.
This Special Issue aims to highlight recent advances in the molecular mechanisms governing the life cycle, host interaction, and pathogenicity of high-risk RNA viruses, with a particular emphasis on structural biology approaches. Contributions addressing viral protein structure, protein–protein interactions, replication and transcription complexes, host–virus interactomes, and mechanisms of immune modulation are especially encouraged. Studies employing techniques such as cryo-electron microscopy, X-ray crystallography, NMR spectroscopy, computational modeling, and integrative structural biology are welcome. In addition, work exploring intrinsically disordered regions, phase separation phenomena, and regulatory networks in viral infection is of particular interest.
By integrating molecular virology with structural insights, this Special Issue seeks to advance our understanding of how highly pathogenic RNA viruses function at the molecular level and to foster the identification of new targets for antiviral intervention and pandemic preparedness.
Dr. Altijana Hromic Jahjefendic
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- high-pathogenicity RNA viruses
- structural virology
- virus–host interactions
- viral replication complexes
- intrinsically disordered proteins
- cryo-electron microscopy
- immune evasion mechanisms
- viral protein structure
- phase separation in viral infection
- antiviral target discovery
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
