Phage: Biocontrol and Biosafety

Dear Colleagues,

Phage therapy is experiencing renewed interest amid the global antimicrobial resistance (AMR) crisis and a shortage of new antibiotics. Advances in sequencing, genomics, and synthetic biology are overcoming previous limitations, spurring research and clinical trials across human health, agriculture, veterinary medicine, and food safety. Numerous countries now permit compassionate use of phage therapy against untreatable multidrug-resistant infections. However, standardized methods, global coordination in regulation, and shared resources—such as phage libraries and GMP facilities—are urgently needed to ensure safe, scalable application.

This Special Issue explores the application of bacteriophages in biocontrol and biosafety. It highlights their role as sustainable alternatives to antibiotics, addressing AMR through targeted bacterial elimination. Themes include therapeutic uses, environmental and agricultural applications, and biosafety assessments. By promoting interdisciplinary collaboration, this Special Issue supports the development of effective, ecologically balanced antimicrobial strategies, contributing to global health security and sustainable practices.

Prof. Dr. Ran Wang
Prof. Dr. Tao He
Guest Editors

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