Structure, Function, and Inhibition of HIV Proteins: Advances in Therapeutic Targets and Drug Discovery
A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "Viral Immunology, Vaccines, and Antivirals".
Deadline for manuscript submissions: 31 July 2027 | Viewed by 59
Special Issue Editors
Interests: proteins; proteases; enzyme kinetics; biological thermodynamics; computational biology; drug design; protein folding; structural biology
Interests: proteins; proteases; structural biology; X-ray crystallography; computational biology; drug discovery and development; nanobiotechnology
Special Issue Information
Dear Colleagues,
The human immunodeficiency virus (HIV) remains a major global health challenge, despite significant advances in antiretroviral therapy. Understanding the structure and function of HIV proteins is critical for identifying novel therapeutic targets and developing next-generation drugs. This Special Issue aims to provide a comprehensive platform for studies exploring the molecular architecture, enzymatic mechanisms, and biological roles of all HIV-related proteins. Emphasis will be placed on the mechanistic insights into protein function and regulation, as well as strategies for inhibition and drug targeting. Contributions that describe rational drug design, structure-based modeling, high-throughput screening, and emerging therapeutic approaches are particularly encouraged. By integrating structural biology, biochemistry, and pharmacology, this Special Issue seeks to highlight advances that can accelerate the discovery of novel inhibitors and therapeutics. We welcome original research articles, reviews, and perspectives that provide innovative insights into HIV protein biology and its translation into effective and targeted interventions, ultimately contributing to improved treatment strategies and the long-term control of HIV infection.
Topics covered in this Special Issue:
- Structure of HIV proteins;
- Function and mechanism;
- Protein inhibition and therapeutic targeting;
- Drug discovery approaches.
Prof. Dr. Yasien Sayed
Dr. Ramesh Pandian
Dr. Joan Okafor-Nwodo
Guest Editors
Manuscript Submission Information
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Keywords
- HIV
- AIDS
- HIV proteins
- protein structure and function
- enzymatic mechanisms
- therapeutic targets
- drug discovery
- protein inhibition
- structure-based drug design
- antiretroviral therapy
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