Structural Biology of Bacteriophages
A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "Bacterial Viruses".
Deadline for manuscript submissions: 16 May 2025 | Viewed by 2976
Special Issue Editors
Interests: cryo-electron microscopy (cryo-EM); pathogen–host interactions; single-stranded RNA bacteriophages
Special Issue Information
Dear Colleagues,
Bacteriophages (phages) are now recognized as promising therapeutic agents against antibiotic-resistant bacteria, emphasizing the importance of their structural biology in elucidating their mechanisms of action. This Special Issue aims to delve into the intricate structures of phages and their interactions with host bacteria, covering various stages of the infection cycle, such as phage capsid assembly, genome packaging/delivery, host receptor binding, antiphage host defense systems, and the host’s lysis. Leveraging modern molecular biology and genomics, which have unveiled the immense diversity of phages, this collection underscores their potential as natural antimicrobials. Recent advances in phage therapy for multidrug-resistant infections highlight the critical need to understand phage structures and their host interactions for developing effective treatments. By assembling cutting-edge research on the structural biology of bacteriophages, this Special Issue illuminates their pivotal role in controlling bacterial populations and their therapeutic potential.
Dr. Junjie Zhang
Dr. Bo Hu
Guest Editors
Manuscript Submission Information
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Keywords
- phage assembly
- phage host recognition
- host defense against phages
- phage genome delivery
- phage lysis
- genome packaging
- host receptors
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