Bacteriophage Lytic Proteins
A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "Bacterial Viruses".
Deadline for manuscript submissions: 31 December 2024 | Viewed by 1039
Special Issue Editor
Interests: mechanisms of bacteriophage-induced lysis; mycobacteriophages; activity of lytic proteins; bacteriophage engineering; development of bacteriophage-based products for therapeutic purposes
Special Issue Information
Dear Colleagues,
The global problem of bacterial resistance to antibiotics has increased the focus on bacteriophage research, particularly due to the potential of these viruses to lyse bacterial pathogens. Phage-induced lysis results from the synthesis of lytic proteins that compromise each barrier of the bacterial cell envelope. These proteins are designed to target bacteriophages’ specific hosts, being structurally diverse and having different activities. Knowledge of their characteristics and understanding their modes of action are important contributions to the development of new tools to kill bacteria and fight multidrug resistance.
This Special Issue, entitled “Bacteriophage Lytic Proteins”, aims to present recent research on any aspect of lysis protein activity, such as holins, endolysins, spanins, and the specific proteins of actinobacteriophages targeting the mycolil layers. Some of its focal points include, but are not limited to, the following:
- Delivery of phage lytic proteins to their targets;
- Understanding endolysin activation and contribution of their functional domains to lysis;
- Mechanisms of phage-induced lysis;
- Bioengineering and applications of phage-derived lytic proteins.
Dr. Madalena Pimentel
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- bacteriophage
- phage lysis
- holins
- endolysins
- spanins
- mycolil esterases
- antimicrobials
