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Toxics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Mechanisms of Disease Caused from Environmental Fluoride and Arsenic Exposures

edited by

Yanmei Yang

, Xiance Sun and

Dapeng Wang

submission deadline 15 Oct 2025 | 7 articles | Viewed by 9136 | Submission Open

Keywords: arsenic; fluorine; human health; toxicity effect; toxicity mechanism; biomarkers; risk assessment

(This special issue belongs to the Section Human Toxicology and Epidemiology)

Novel Remediation Strategies for Soil Pollution

edited by Jiaqi Shi and Tingting Fan

submission deadline 15 Oct 2025 | 6 articles | Viewed by 7254 | Submission Open

Keywords: soil remediation; advanced oxidative process; soil risk assessment; bioremediation; combined remediation of soil and groundwater; development of innovative remediation material

(This special issue belongs to the Section Ecotoxicology)

Interventions, Practices, and Policies to Reduce Particulate Matter Air Pollution Exposure and Health Outcomes

edited by

Douglas Brugge

and Shir Ginzburg

submission deadline 15 Oct 2025 | Viewed by 187 | Submission Open

Keywords: exposure reduction; health outcomes; interventions; particulate matter; randomized trials

(This special issue belongs to the Section Air Pollution and Health)

Hazardous Effects of Pesticides on Human Health—2nd Edition

edited by

Balázs Ádám

Lode Godderis

and

Radu-Corneliu Duca

submission deadline 17 Oct 2025 | 2 articles | Viewed by 4342 | Submission Open

Keywords: pesticide; product formulation; chronic low-level exposure; comparative toxicological assessment; human health effect; genotoxicity; carcinogenicity; teratogenicity

(This special issue belongs to the Section Agrochemicals and Food Toxicology)

Soil Heavy Metal Pollution and Human Health

edited by

Ping Xiang

and Chengchen Wang

submission deadline 20 Oct 2025 | 3 articles | Viewed by 2704 | Submission Open

Keywords: heavy metals; human health; food safety; monitoring techniques; pretreatment methods; contaminant control approaches

(This special issue belongs to the Section Metals and Radioactive Substances)

Emerging Methodologies in Toxicology for Environmental Safety Assessment

edited by

Melissa Faria

Juliette Bedrossiantz

and

Marcelino Miguel Guedes de Jesus Oliveira

submission deadline 20 Oct 2025 | 2 articles | Viewed by 1481 | Submission Open

Keywords: toxicology; chemical safety; emerging contaminants; integrated approaches; predictive modeling; new methodology approaches; high-throughput screening; adverse-outcome pathways; risk assessment; One Health

Ecological Remediation of Heavy Metal-Polluted Environment

edited by Ruyi Yang,

Yongjie Wang

and Meng Zhu

submission deadline 20 Oct 2025 | Viewed by 359 | Submission Open

Keywords: heavy metal pollution; ecological remediation; emerging techniques; rhizosphere microecological processes; remediation efficiency optimization; ecosystem health assessment post-remediation; remediation policies and standards

(This special issue belongs to the Section Toxicity Reduction and Environmental Remediation)

Toxicological Effects of Natural Products Derived from Plants or Animals Used in Therapeutical Treatments

edited by

Laura Narciso

and Carla Raggi

submission deadline 24 Oct 2025 | Viewed by 266 | Submission Open

Keywords: natural products; plant; animal; therapeutic effect; toxicological evaluation; cytotoxicity; genotoxicity; reproductive toxicity

Genotoxicity of Environmental Pollutants: From Mechanistic Insights to Risk Assessment

edited by

Antonio Cascajosa-Lira

and

Remedios Guzmán-Guillén

submission deadline 24 Oct 2025 | Viewed by 142 | Submission Open

Keywords: mutagenicity; carcinogenicity; Ames; DNA damage; risk assessment; environmental pollutants; micronucleus

(This special issue belongs to the Section Human Toxicology and Epidemiology)

Transformation Process and Toxic Effects of Pollutants in Agricultural Environment

edited by

Changbo Zhang

, Liang Peng and Weijie Xue

submission deadline 25 Oct 2025 | 7 articles | Viewed by 8709 | Submission Open

Keywords: heavy metal pollution; emerging contaminants; contamination remediation; contaminated farmland; ecotoxicological aspects of the agro-environment; microplastics; toxicity

(This special issue belongs to the Section Toxicity Reduction and Environmental Remediation)

Prenatal Chemical Exposure and Child Health Outcomes

edited by

Maria José Rosa

, Cecilia Alcala and Jamil Lane

submission deadline 31 Oct 2025 | 4 articles | Viewed by 5646 | Submission Open

Keywords: chemical exposure; children’ s health; birth outcomes; environmental mixtures; prenatal exposure

(This special issue belongs to the Section Reproductive and Developmental Toxicity)

Exploring Toxicity, Metabolism, and Transformation of Organic Pollutants

edited by

Jianteng Sun

and

Xiaolong Yu

submission deadline 31 Oct 2025 | 4 articles | Viewed by 5460 | Submission Open

Keywords: emerging organic pollutants; soil pollution; migration and biotransformation; environmental occurrence; metabolism; bioaccumulation; transformation products

(This special issue belongs to the Section Toxicity Reduction and Environmental Remediation)

Characteristics, Sources, Occurrence and Toxicological Mechanisms of Environmental Pollutants in Aquatic Systems

edited by Desheng Pei and Panpan Jia

submission deadline 31 Oct 2025 | 2 articles | Viewed by 3819 | Submission Open

Keywords: aquatic systems; environmental pollutants; neurodevelopmental and developmental toxicity; animal models; exposure and detection methods; human health; molecular mechanisms

Health Effects of Exposure to Environmental Pollutants—2nd Edition

edited by Guang Jia and

Zhangjian Chen

submission deadline 31 Oct 2025 | 4 articles | Viewed by 3672 | Submission Open

Keywords: toxic effects; toxic mechanism; biomarkers; multi-omics techniques; nanotoxicity; heavy metals

(This special issue belongs to the Section Human Toxicology and Epidemiology)

Biomonitoring of Toxic Elements and Emerging Pollutants

edited by

Miguel Motas Guzmán

, Pedro Andreo-Martínez and Juan Jose Ramos

submission deadline 31 Oct 2025 | 2 articles | Viewed by 3272 | Submission Open

Keywords: environmental health risks; bioaccumulation; biomonitoring; ecotoxicity; emerging contaminants; one health; biological effect monitoring; laboratory tests and validation

(This special issue belongs to the Section Emerging Contaminants)

Microplastics in Atmospheric, Aquatic, and Soil Ecosystems: Occurrence, Impacts, and Innovations in Detection and Mitigation

edited by Jheng-Jie Jiang and Tetsuro Agusa

submission deadline 31 Oct 2025 | 1 articles | Viewed by 3222 | Submission Open

Keywords: microplastics; nanoplastics; atmospheric microplastics; aquatic ecosystems; soil microplastics; analytical techniques; ecotoxicology; human health; remediation strategies; policy implications

Environmental Contaminants and Human Health—2nd Edition

edited by Lin Xu, Penghui Li and Xingchen Zhao

submission deadline 31 Oct 2025 | 3 articles | Viewed by 2781 | Submission Open

Keywords: environmental contaminants; exposure; health effects; risk estimation; toxicological effect; food chain; microplastics; emerging pollutants; nanotoxicology

(This special issue belongs to the Section Exposome Analysis and Risk Assessment)

Advances in Monitoring, Transformation and Ecological Risk Assessment of Pharmaceuticals and Personal Care Products in Aquatic Environments

edited by Haohan Yang and

Jun Wu

submission deadline 31 Oct 2025 | 3 articles | Viewed by 2294 | Submission Open

Keywords: PPCPs; natural organic materials; micro/nanoplastics; bioavailability; ecological risk assessment; biological effects; transfromation and metabolic pathways

(This special issue belongs to the Section Emerging Contaminants)

Pharmaceutical Pollutants: Environmental Fate, Risk Assessment and Sustainable Solutions

edited by Guixiang Zhang

submission deadline 31 Oct 2025 | 1 articles | Viewed by 962 | Submission Open

Keywords: pharmaceuticals; antibiotic resistance genes; soil; water; sediments; environmental fate; risk assessment; sustainable solutions

(This special issue belongs to the Section Emerging Contaminants)

Pollutants in Soil and Groundwater, Effects and Strategies for Comprehensive Risk Assessment

edited by

Zhongkang Yang

, Wenhan Cheng, Zhuding Chu and

Ruijuan Qu

submission deadline 31 Oct 2025 | 1 articles | Viewed by 946 | Submission Open

Keywords: soil and groundwater pollution; risk assessment; ecological and human health impacts; remediation strategies; emerging pollutants; environmental monitoring

(This special issue belongs to the Section Exposome Analysis and Risk Assessment)

Oxidative Degradation and Toxicity of Environmental Pollutants

edited by

Jianfei Sun

and

Bo Wei

submission deadline 31 Oct 2025 | 1 articles | Viewed by 856 | Submission Open

Keywords: oxidative degradation; toxicity; environmental pollutants; volatile organic compounds; reaction mechanisms; kinetics; advanced oxidation process

(This special issue belongs to the Section Emerging Contaminants)

Assessing Contaminants in Food: Dietary Exposure, Human Health Risks, and Emerging Challenges

edited by

Virgínia Cruz Fernandes

submission deadline 31 Oct 2025 | Viewed by 188 | Submission Open

Keywords: environmental exposure; toxic chemicals; emerging pollutants; micro(nano)plastics; analytical methods; biomonitoring; health risks; human health; One Health

(This special issue belongs to the Section Emerging Contaminants)

Effects and Mechanism of Endocrine Disruption and Reproductive Abnormality of Emerging Pollutant

edited by Liping Lu, Yu Han,

Shixuan Cui

and

Tingjie Zhan

submission deadline 31 Oct 2025 | Viewed by 152 | Submission Open

Keywords: environmental toxicology; endocrine disruption; molecular mechanism; emerging pollutants; nuclear receptor; computational toxicology

(This special issue belongs to the Section Reproductive and Developmental Toxicity)

Nanomaterials Adsorption and Removal of Pollutants and Environmental Remediation

edited by Yinqing Zhang and

Jingzhen Wang

submission deadline 31 Oct 2025 | Viewed by 145 | Submission Open

Keywords: nanomaterials; pollutant adsorption; pollutant removal; environmental remediation; toxicity reduction

(This special issue belongs to the Section Toxicity Reduction and Environmental Remediation)

Human Exposure and Computational Modeling of Persistent Organic Pollutants (POPs)

edited by

Deepika Deepika

and

Vikas Kumar

submission deadline 10 Nov 2025 | 1 articles | Viewed by 1322 | Submission Open

Keywords: human biomonitoring; computational modeling; OMICS analysis; risk assessment; mechanism of action; adverse outcome pathways; human health predictive modeling machine learning new approach methodology

(This special issue belongs to the Section Novel Methods in Toxicology Research)

Toxicity and Safety Assessment of Exposure to Heavy Metals

edited by

Cristina Carvalho

and

Michael Aschner

submission deadline 14 Nov 2025 | 3 articles | Viewed by 4744 | Submission Open

Keywords: human exposure to metals; environmental contamination; metals’ biogeochemistry; food metal contaminants; toxic effects of metals; metals’ mechanisms of toxicity; risk assessment; biomarkers; metallodrugs; metal ion chelators

(This special issue belongs to the Section Metals and Radioactive Substances)

From Low-Tier to Individual Effects of Emerging Pollutants: Integrative Approaches to Ecotoxicological Assessments—2nd Edition

edited by

Tiago Simoes

Hugo Monteiro

and

Nuno Ferreira

submission deadline 15 Nov 2025 | 2 articles | Viewed by 1844 | Submission Open

Keywords: biomarkers; ecotoxicology; emerging pollutants; biological effects; mode of action; integrative analysis; analytical methods; sub-lethal endpoints

(This special issue belongs to the Section Ecotoxicology)

Emerging Pollutants in the Air and Health Risks

edited by

Qi Zhao

and

Gongbo Chen

submission deadline 20 Nov 2025 | 5 articles | Viewed by 8918 | Submission Open

Keywords: emerging pollutants; air pollution; exposure assessment; risk assessment; novel methodologies; statistical modeling; toxic mechanisms

(This special issue belongs to the Section Exposome Analysis and Risk Assessment)

Toxicity Assessment and Safety Management of Nanomaterials

edited by

Guotao Peng

submission deadline 20 Nov 2025 | 4 articles | Viewed by 3979 | Submission Open

Keywords: nanotoxicology; engineered nanomaterials; micro- and nanoplastics; nano– bio interactions; biotransformation; structure– activity relationship; health risks

(This special issue belongs to the Section Emerging Contaminants)

Plant Responses to Heavy Metal

edited by Yanqun Zu

submission deadline 20 Nov 2025 | 2 articles | Viewed by 1208 | Submission Open

Keywords: heavy metals; plant; soil pollution; phytoremediation; mechanism; regulation and control

New Insights into the Environmental Behaviour and Toxicity of Critical and Strategic Metals in Aquatic Ecosystems

edited by

Maikel Rosabal

, Séverine Le Faucheur and

Xu Yang

submission deadline 20 Nov 2025 | Viewed by 195 | Submission Open

Keywords: critical and strategic minerals (CSMs); environmental behavior; toxicological risk assessment; bioavailability and bioaccumulation; aquatic ecosystems; omics techniques

(This special issue belongs to the Section Metals and Radioactive Substances)

Emission and Exposure Assessment of Volatile Organic Compounds

edited by

Besis Athanasios

and

Dimitris Margaritis

submission deadline 20 Nov 2025 | Viewed by 183 | Submission Open

Keywords: volatile organic compounds (VOCs); secondary organic aerosols (SOAs); emission sources; monitoring techniques; exposure assessment; human health risk; VOC mitigation strategies; indoor and outdoor air quality; air pollution

(This special issue belongs to the Section Air Pollution and Health)

Exposure, Pathways and Assessment of (Eco)Toxicity of Nanomaterials

edited by

Gang Liang

submission deadline 20 Nov 2025 | Viewed by 149 | Submission Open

Keywords: toxicity; risk assessment; ecotoxicological effect; analytical methods; emerging nanomaterials

(This special issue belongs to the Section Ecotoxicology)

Multi-Media Environmental Pollution and Health Risks: Tracing, Effects, and Collaborative Governance

edited by

Dexin Liu

Jianbiao Peng

and Lihong Ren

submission deadline 21 Nov 2025 | 4 articles | Viewed by 2443 | Submission Open

Keywords: atmosphere; water; soil; sediment; pollutants; source apportionment; risk assessment; human exposure; pollution control; environmental pollution; health risks; heavy metal; environmental toxicology; ecotoxicology

(This special issue belongs to the Section Toxicity Reduction and Environmental Remediation)

New Approach Methodologies in Environmental Risk Assessment of Chemical Contaminants

edited by

Carlos Barata

submission deadline 21 Nov 2025 | Viewed by 179 | Submission Open

Keywords: approaches for pollution assessment; ecotoxicology; ecological effects; new approach methodologies; chemical toxicity; chemical contaminants; risk assessment

(This special issue belongs to the Section Ecotoxicology)

Neuronal Injury and Disease Induced by Environmental Toxicants

edited by

Jun Wang

and

Guixiang Ji

submission deadline 25 Nov 2025 | 6 articles | Viewed by 8831 | Submission Open

Keywords: neurotoxicology; neural injury and mechanisms; chemical exposure; neurodegenerative diseases; psychiatric disorders; toxicomics; toxic intervention

(This special issue belongs to the Section Neurotoxicity)

State-of-the-Art Environmental Chemical Exposomics and Metabolomics—2nd Edition

edited by

Minjian Chen

submission deadline 25 Nov 2025 | 4 articles | Viewed by 7210 | Submission Open

Keywords: exposomics; metabolomics; exposome; exposure; metabolome; metabolism; health; toxicity

(This special issue belongs to the Section Exposome Analysis and Risk Assessment)

Emissions, Environmental Behavior, Pollution Distribution, Modeling, and Risk Assessment of Persistent Organic Pollutants (POPs)

edited by Ye Huang

submission deadline 25 Nov 2025 | 2 articles | Viewed by 6408 | Submission Open

Keywords: persistent organic pollutants (POPs); emission inventory; environmental behavior; pollution distribution; risk assessment; modeling techniques; remediation strategies

(This special issue belongs to the Section Emerging Contaminants)

Airway Exposure to Pollution from Ambient Particulate Matter (PM) and Health Effects

edited by

Gloria Melzi

and

Yuewei Liu

submission deadline 28 Nov 2025 | 3 articles | Viewed by 2627 | Submission Open

Keywords: air pollution; particulate matter (PM); respiratory health; airway inflammation; oxidative stress; in vitro toxicology; alternative testing methods; cell culture models; health risk assessment

(This special issue belongs to the Section Air Pollution and Health)

Health Risk Assessment for Food Contaminants: Exposure and Human Toxicology

edited by

Yu-Syuan Luo

and

Nan-Hung Hsieh

submission deadline 28 Nov 2025 | Viewed by 129 | Submission Open

Keywords: food contaminants; health risk assessment; exposure modeling; toxicology; new approach methodologies (NAMs)

(This special issue belongs to the Section Exposome Analysis and Risk Assessment)

Biological Risk Monitoring of Exposure to Chemical Pollutants and/or Physical Agents: 2nd Edition

edited by

Mirta Milić

and

Nursen Basaran

submission deadline 29 Nov 2025 | 1 articles | Viewed by 3021 | Submission Open

Keywords: biomarkers of effect; biomarkers of exposure; biomarkers of susceptibility; DNA damage and repair; meta-analysis; biomonitoring; exposure; toxicokinetics and modes of action; risk assessment; epidemiology

(This special issue belongs to the Section Exposome Analysis and Risk Assessment)

Concentration of VOCs in the Atmosphere and Its Environmental Exposure

edited by

Xinlei Ge

and

Ming Wang

submission deadline 30 Nov 2025 | 4 articles | Viewed by 3756 | Submission Open

Keywords: VOCs; health risk assessment; exposure assessment; source identification; environmental impact

(This special issue belongs to the Section Emerging Contaminants)

Identification of Emerging Pollutants and Human Exposure

edited by

Xiaotu Liu

and

Ting Wu

submission deadline 30 Nov 2025 | 2 articles | Viewed by 2621 | Submission Open

Keywords: emerging contaminants; remediation strategies; non-targeted analysis; biomonitoring; exposome; risk assessment

Human Biomonitoring Studies: Environmental Pollution and Possible Risks to Human Health

edited by

Valentina Marra

Anna Maria Ingelido

and Silvia Valentini

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1204 | Submission Open

Keywords: air pollution human biomonitoring; biological matrices (serum; urine; milk); exposure assessment; exposure biomarkers; reproductive toxicity; adults; children; reproductive age; emerging compounds; persistent organic compounds

(This special issue belongs to the Section Exposome Analysis and Risk Assessment)

Biological Effects and Mechanisms of Environmental Endocrine Disruptors

edited by Liting Zhou

submission deadline 30 Nov 2025 | 1 articles | Viewed by 943 | Submission Open

Keywords: environmental endocrine disruptors; epidemiological research; health effects; mixed exposure; emerging experimental models; mechanism

(This special issue belongs to the Section Human Toxicology and Epidemiology)

Hazardous Pollutants in Marine Ecosystems

edited by

Maria Luisa Vannuccini

and Inmaculada Varó

submission deadline 30 Nov 2025 | 1 articles | Viewed by 642 | Submission Open

Keywords: ecotoxicology; nanomaterials; bioaccumulation; biotransformation; biomonitoring; POPs; PAHs

Emerging Pollutants in the Aquatic Ecosystems: Occurrence, Fate and Effects on the Dissemination of Antibiotic Resistance Genes

edited by Lijun Zhou and Liangying He

submission deadline 30 Nov 2025 | Viewed by 272 | Submission Open

Keywords: antibiotics; antibiotic resistance genes; emerging pollutant; PPCPs; biocides; occurrence; ecological risk; horizontal gene transfer

(This special issue belongs to the Section Emerging Contaminants)

Migration and Transformation of Emerging Pollutants and Improvement of Water Quality

edited by Shibao Lu and

Liang Pei

submission deadline 30 Nov 2025 | Viewed by 198 | Submission Open

Keywords: pollutant fate and transport; emerging contaminants; water remediation technologies; environmental nanotechnology; hydrobiogeochemical cycles; smart water management

From Detection to Risk: Data-Driven Advances in Analytical Chemistry and Toxicology

edited by

Nikiforos Alygizakis

submission deadline 30 Nov 2025 | Viewed by 176 | Submission Open

Keywords: analytical chemistry; computational mass spectrometry; toxicology; exposure assessment; chemical prioritization; mixture toxicity; environmental risk assessment

(This special issue belongs to the Section Novel Methods in Toxicology Research)

Fish Physiological Responses to Environmental Stressors

edited by

Jun Wang

submission deadline 30 Nov 2025 | 1 articles | Viewed by 136 | Submission Open

Keywords: fish ecotoxicology; physiological disruption; oxidative stress biomarkers; ecological risk assessment; bioaccumulation dynamics; endocrine disruption; population changes

(This special issue belongs to the Section Ecotoxicology)

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