Special Issue "Behavioral Impairment in Aquatic Organisms Exposed to Neurotoxic Pollutants"
Deadline for manuscript submissions: 31 July 2021.
Interests: analytical chemistry; aquatic toxicology; environmental risk assessment; toxicogenomics
Interests: toxicology; biomarkers; environmental science; biological science; behaviour and neurotoxicity
It has been estimated that up to 30,000 of commercially used chemicals may have neurotoxic potential. Neuroactive chemicals, including neurotoxic pesticides, pharmaceuticals, and illicit drugs, are the largest group of micropollutants present in European rivers, where nearly 30% of all detected chemicals were linked to neurotoxicity. Furthermore, neurotoxic actions of environmental contaminants on non-target species have been determined. It is suspected that such actions include changes in the behavior of organisms. For example, environmental pollutants such as trace metals and organic toxicants have been reported to increase fish susceptibility to predation, antidepressant drug altered sex mating behavior in fish, phototaxis and feeding in amphipods, cladocerans and worms, altered mobility of snails, memory, cognitive function, and the ability to camouflage in cuttlefish at environmental relevant concentrations.
This Special Issue on “Behavioral Impairment in Aquatic Organisms Exposed to Neurotoxic Pollutants” aims to highlight research on behavioral analysis in aquatic organisms using automated image analysis systems. Studies that anchor behavioral impairment with molecular markers, and also with population level effects will be preferred. Research addressing exposure to environmental relevant concentrations of pollutants will receive priority. Methodological studies developing new tools for the automated behavioral analysis in aquatic organisms are also encouraged.
Authors are invited and welcome to submit original research papers, reviews, and short communications.
Dr. Demetrio Raldúa
Dr. Carlos Barata
Dr. Melissa Faria
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Behavioral analysis
- Neuroactive chemicals
- Neuroendocrine disruption
- Environmental relevant concentrations
- Aquatic organisms
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
Title: Psychoactive drugs in the aquatic environment: are they of concern?
Authors: Luigi Margiotta-Casaluci; John P. Sumpter
Affiliation: Brunel University London, UK
Title: A transient exposure to sub-lethal concentrations of a pesticide mixture (chlorpyrifos-difenoconazole) caused different responses in fish species from different trophic levels of the same community
Authors: Sergei Redondo-López; Ana C. León; Katherine Jiménez; Karla Solano; Kinndle Blanco-Peña; Freylan Mena
Affiliation: Instituto Regional de Estudios en Sustancias Tóxicas / Central American Institute for Studies on Toxic Substances (IRET
Abstract: Pesticide contamination of aquatic ecosystems is a major concern in agricultural landscapes. The improvement of ecotoxicological methods should address the assessments of pesticide mixtures and the early effects caused in biota by exposure to sub-lethal concentrations. A multi-level biomarker approach was used to assess the effects of a transient exposure to a pesticide mixture on two freshwater mesoamerican fish species. Fish, Parachromis dovii, and Poecilia gillii were shortly (48h) exposed to a mixture of sublethal concentrations of chlorpyrifos (5 µg/L) and difenoconazole (325 µg/L). Transcriptomic induction of cyp1A, as well as EROD and GST activities, were measured as biotransformation-related biomarkers. ChE activity was assessed as a neurotoxic effect biomarker. Resting metabolic rate (RMR) was measured as a physiological biomarker, and the movement of fish in a dark-light environment was assessed as a behavior biomarker. The exposure to the pesticides had different effects on the fish: P. gillii had evident induction of biotransformation phase I, with significant induction of cyp1A transcription and increased EROD activity, accompanied by ChE inhibition in muscle and an increased permanence in the light side of the dark-light environment. On the other hand, P. dovii only showed a significant induction of cyp1A, without significant evidence of neurotoxicity or changes in behavior. None of the species showed physiological changes after the exposure. This rapid, multi-level evaluation, applied to two fish species that share the environment and a predator-prey relationship, demonstrated that a short, sub-lethal exposure to widely used pesticides has the potential to cause impairment in the trophic structure of the community.