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Toxics
Special Issues
Understanding Contaminant Bioaccumulation and Toxicokinetics: A One Health Perspective
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Understanding Contaminant Bioaccumulation and Toxicokinetics: A One Health Perspective

A special issue of Toxics (ISSN 2305-6304). This special issue belongs to the section "Ecotoxicology".

Deadline for manuscript submissions: 10 September 2025 | Viewed by 431

Special Issue Editors

Dr. Diogo N. Cardoso

E-Mail Website
Guest Editor
CESAM—Centre for Environmental and Marine Studies, Department of Biology, University of Aveiro, 3810-193 Aveiro, Portugal
Interests: ecotoxicology; ecological risk assessment; bioaccumulation assays; insects; novel protein sources; toxicokinetic modeling; contaminants transfer; circularity; sustainable agriculture
Special Issues, Collections and Topics in MDPI journals
Dr. Ana Rita R. Silva

E-Mail Website
Guest Editor
CESAM—Centre for Marine and Environmental Studies, Department of Biology, University of Aveiro, 3810-193 Aveiro, Portugal
Interests: zero-waste; circularity; sustainability; ecotoxicology; chemical mixtures; multigenerational; genotoxicity; mesocosms; environmental risk assessment; climate and global changes; science dissemination
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We are pleased to announce that the Special Issue (SI) entitled “Understanding contaminant bioaccumulation and toxicokinetics: A One Health Perspective” is now open for submissions.

This SI seeks to find relevant works with the bioaccumulation of (emerging) contaminants in terrestrial and aquatic environments, emphasizing their potential consequences for human health. Studies involving toxicokinetic modeling or similar modeling approaches are especially valued.

We encourage works that explore how bioaccumulating contaminants in terrestrial and aquatic organisms could impact or threaten human health. Such research should also promote solutions and mitigation strategies for reducing exposure risk. Realistic contamination scenarios and relevant environmental concentrations are always preferable.

Food and feed safety-related studies are also welcome, particularly those supporting regulatory frameworks and livestock management strategies to foster sustainable and safe food and feed supply chains. Additionally, we invite research aligned with circular economy and zero-waste principles, where reducing contaminant exposure through sustainable resource use can promote environmental, animal, and human health under the One Health framework.

We look forward to receiving your contributions.

Dr. Diogo N. Cardoso
Dr. Ana Rita R. Silva
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • bioaccumulation
  • toxicokinetics
  • emerging contaminants
  • terrestrial and aquatic ecosystems
  • trophic transfer
  • food safety
  • edible organisms
  • human exposure
  • regulatory limits
  • environmental health

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Published Papers (1 paper)

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Research

17 pages, 1560 KiB  
Article
The Association Between Maternal Dietary Intake and the Risk of Heavy Metals in Human Breast Milk in Korea
by Nalae Moon, Su Ji Heo, Seungyoung Park, Hosub Im and Ju Hee Kim
Toxics 2025, 13(5), 381; https://doi.org/10.3390/toxics13050381 - 8 May 2025
Viewed by 310
Abstract
Heavy metals (HMs) persist in the environment and enter the human body via various pathways. Once stored in adipose tissue, they can be transferred to breast milk, posing risks to infants. Moreover, maternal diet plays a key role in influencing HM levels in [...] Read more.
Heavy metals (HMs) persist in the environment and enter the human body via various pathways. Once stored in adipose tissue, they can be transferred to breast milk, posing risks to infants. Moreover, maternal diet plays a key role in influencing HM levels in breast milk. The aim of this study was to measure the concentration of HMs, including lead (Pb), cadmium (Cd), mercury (Hg), and arsenic (As), in the breast milk of Korean mothers, assess their potential health risks, and identify maternal dietary factors influencing HM concentration in breast milk. Survey data on maternal–infant pairs and breast milk samples from 209 healthy lactating mothers were collected between January and March 2023. Trained nurses manually expressed the breast milk to prevent external contamination, and maternal dietary intake was systematically assessed using the 24 h recall method. The concentrations of Pb, Cd, Hg, and As were measured, and a risk assessment was conducted using the estimated daily intake hazard quotient. A multiple linear regression model was employed to evaluate the association between the HMs in breast milk and maternal dietary factors. Cd was detected in 99% of the breast milk samples, and high detection rates were observed for Hg (97%), As (89%), and Pb (79%). Arsenic was the largest contributor to the potential health risks of HM-contaminated breast milk. Positive associations were observed between Pb concentration and legume and seaweed consumption, Cd concentration and vegetable and seaweed consumption, Hg concentration and sugar intake, and As concentration and meat intake. This study highlights that maternal dietary intake is closely linked to HM concentrations in breast milk, and elevated As levels potentially pose health risks to infants. These findings underscore the importance of adopting a healthy diet to reduce HM exposure in breast milk and to promote safer breastfeeding practices. Full article
(This article belongs to the Special Issue Understanding Contaminant Bioaccumulation and Toxicokinetics: A One Health Perspective)
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