Current Developments in Microbial Ecotoxicology of Priority, Legacy and Emerging Pollutants

A special issue of Toxics (ISSN 2305-6304). This special issue belongs to the section "Ecotoxicology".

Deadline for manuscript submissions: closed (20 November 2022) | Viewed by 2302

Special Issue Editors


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Guest Editor
1. ISEP-School of Engineering, Polytechnic Institute of Porto, Porto, Portugal
2. Centre of Biological Engineering, University of Minho, Braga, Portugal
Interests: aquatic ecotoxicology; effect of environmental contaminants (emerging organic pollutants, heavy metals, and engineered nanomaterials) on yeast and algae physiology; mode of action of pollutants; development and application of bioassays to assess aquatic pollution; oxidative stress

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Guest Editor
Centre of Biological Engineering, University of Minho, Braga, Portugal
Interests: environmental toxicology; microalgae and yeast, contaminants of emerging concern (antibiotics, biocides, pesticides, heavy metals); development and application of bioassays for assessing aquatic pollution; mixture toxicology; elucidation of the mechanisms of action of pollutants on microorganisms and adaptive pathways to combat oxidative stress

Special Issue Information

Dear Colleagues,

Microbial cells can be exposed to multiple stressors, including pharmaceuticals and personal care products, pesticides, heavy metals, nanomaterials and several other pollutants that enter the environment by design or by ineffective waste treatment. It is known that microorganisms are sensitive indicators of environmental pollution being largely used in ecotoxicity assessment due to their fast response to toxics, ease to culture and maintenance in the laboratory and their use does not raise ethical issues. However, most of the time, it is not easy to detect subtle, non-lethal effects resulting from low level exposure to pollutants.

The big efforts in microbial toxicity must be directed towards to the: 1) development of new tools that allow the early detection of the effects of pollutants, before being expressed by traditional endpoints like growth or viability; 2) identification of the main targets of pollutants in order to allow the elucidation of their mechanisms of action on microorganisms (of different trophic levels of the food web) and the adaptive pathways to combat polluting stress.

Thus, we are pleased to invite you to contribute with an original research paper or a review paper this Special Issue. Research areas may include (but are not limited to) the following:

  • Toxicity effects of priority, legacy and emerging pollutants in microorganisms;
  • Microbial targets/effects of toxics at different biological levels (molecular, cellular);
  • New toxicity endpoints/tools;
  • Development of new bioassays and bioindicators;
  • Study of single and mixture of toxics;
  • Toxicity studies with realistic concentrations of pollutants;
  • Elucidation of the mechanisms of action underlying pollutants toxicity;
  • Oxidative damage;
  • Antioxidant defence mechanisms (non- and enzymatic);
  • Omics approaches in toxicological studies.

We look forward to receiving your contributions.

Dr. Eduardo V. Soares
Dr. Manuela Dias Machado
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • priority, legacy and emerging pollutants
  • algae, bacteria, fungi and protozoa
  • mode of action of toxics
  • targets of pollutants in microorganisms
  • single and mixtures of toxics
  • risk assessment
  • omics
  • "early" toxicity endpoints
  • development of innovative ecotoxicological endpoints
  • new bioassays and bioindicators

Published Papers (1 paper)

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Research

12 pages, 1009 KiB  
Article
Antibiotic Toxicity Isolated and as Binary Mixture to Freshwater Algae Raphidocelis subcapitata: Growth Inhibition, Prediction Model, and Environmental Risk Assessment
by Fang Chang, Malan Yi, Huiting Li, Jiangnan Wang, Xuefeng Zhao, Xiaoyue Hu and Qianju Qi
Toxics 2022, 10(12), 739; https://doi.org/10.3390/toxics10120739 - 29 Nov 2022
Cited by 6 | Viewed by 1655
Abstract
Antibiotics in aqueous environments can have extremely adverse effects on non-targeted organisms. However, many research projects have only focused on the toxicological evaluation of individual antibiotics in various environments. In the present work, individual and binary mixture toxicity experiments have been conducted with [...] Read more.
Antibiotics in aqueous environments can have extremely adverse effects on non-targeted organisms. However, many research projects have only focused on the toxicological evaluation of individual antibiotics in various environments. In the present work, individual and binary mixture toxicity experiments have been conducted with the model organism Raphidocelis subcapitata (R. subcapitata), and a mixture concentration-response curve was established and contrasted with the estimated effects on the basis of both the concentration addition (CA) and the independent action (IA) models. In addition, different risk assessment methods were used and compared to evaluate the environmental risk of binary mixtures. The toxic ranking of the selected antibiotics to R. subcapitata was erythromycin (ERY) > sulfamethoxazole (SMX) > sulfamethazine (SMZ). In general, the conclusion of this study is that the adverse effects of binary mixtures are higher than the individual antibiotics. The CA model and RQSTU are more suitable for toxicity prediction and risk assessment of binary mixtures. This study reveals the potential ecological risks that antibiotics and their mixtures may pose to water ecosystems, thus providing scientific information for environmental quality regulation. Full article
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