Mechanisms of Toxicity of Chemical Compounds and Natural Compounds
A special issue of Toxics (ISSN 2305-6304). This special issue belongs to the section "Drugs Toxicity".
Deadline for manuscript submissions: 24 April 2026 | Viewed by 2
Special Issue Editor
Interests: in vitro and in vivo studies; agrochemicals; medicinal plant extracts; cytotoxicity; toxicology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Knowledge, understanding, and analysis of the toxicity mechanisms of chemical compounds, such as xenobiotics or natural compounds, are essential for assessing risks to human health, animal health, and the environment.
This Special Issue is dedicated to acute or chronic toxicity studies based on standardized protocols such as those of the OECD, which address the toxic effects of both chemical and natural substances using in vivo and in vitro models, mainly through experimental testing.
It includes research focused on the characterization of acute or chronic cytotoxic, genotoxic, hepatotoxic, and neurotoxic effects, among others, as well as mechanistic studies exploring molecular pathways, oxidative stress, mitochondrial dysfunction, inflammation, and programmed cell death. Contributions related to new toxicological assessment methodologies, biomarkers of exposure and toxicity, and alternative strategies to animal experimentation are also valued. This Special Issue aims to provide a platform for the exchange of knowledge between scientists, regulatory and legislative agencies, and health professionals, promoting a better understanding of the toxicological and safety impact of the different compounds to which all species of toxicological interest are constantly exposed.
Dr. José Luis Rodríguez Gutiérrez
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- chemical compounds
- natural compounds
- toxicity mechanisms
- in vivo
- in vitro
- assessing risks
- toxicological assessment
- exposure
- health
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