Pesticides and Human Health: Between Toxicology and Epidemiology

Dear Colleagues,

The purpose of this Special Issue is to contribute, with novel information and integrative approaches, to the knowledge on the health effects of pesticides. It is open to relevant information obtained using different experimental models (e.g., in vitro, in vivo animal models, and in silico models) as well as epidemiological and other human-based studies. Special attention will be given to the integration of toxicological and epidemiological information and to the challenging assessment of the potential endocrine-disruptive properties of these compounds. As a significant part of the exposome, which plays an equally important role in the risk of disease development as the genome itself, pesticide exposure and their significant toxicity to human health represent a very relevant and ongoing actual issue. In spite of extensive research having been conducted, there are still many open questions regarding the specific mechanisms of action of pesticides and their actual impact on human health. Endocrine-disrupting potential has been confirmed for many pesticides today; the interaction of pesticides with the endocrine system may affect fertility and development, metabolism, induce endocrine-mediated tumors, etc. Endocrine disruptors may have specific time windows with high vulnerability, and today, it is widely accepted that early life exposure can influence health outcomes later in life through the “Developmental Origins of Health and Disease (DOHaD)” hypothesis.

By selecting interesting manuscripts that contribute novel information related to toxicology, epidemiology, and approaches for the integration of both disciplines, this Special Issue will provide us with some new insights into the health risk and endocrine-disruptive properties of pesticides, which have not been investigated in sufficient detail and published in the existing literature.

Dr. Anja Katić
Dr. Jose V. Tarazona
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• pesticides
• human exposure
• toxicity
• endocrine disruptors
• hormones
• children
• experimental models
• risk
• safety