Application of Liquid Chromatography in Pharmaceutical and Toxicological Analysis

Dear Colleagues,

We are pleased to invite you to publish in this Special Issue focused on the application of liquid chromatography in pharmaceutical and toxicological analysis.

In pharmaceutical and toxicological fields, chromatography is one of the most used analytical methods for the identification and quantification of xenobiotics and their metabolites.

Different chromatographic techniques have been developed for the qualitative-quantitative determination of drugs according to their characteristics. Among these techniques, in particular, High-Performance Liquid Chromatography (HPLC) is the most used for pharmaceutical and toxicological purposes. The success of liquid chromatography in the development of rapid and precise analytical methods is that it provides good specificity and sensitivity. Sample pretreatment is an important factor to be considered to provide a selective chromatographic analysis. The use of specific purification techniques provides a sample that is relatively free of interferences, compatible with the analytical method, and that does not damage instrumentation. It is further desirable to concentrate the analytes for improved detection.

This Special Issue aims to provide an overview of applications of liquid chromatography in pharmaceutical and toxicological analysis, including both human and veterinary medicine.

In this Special Issue, original research articles and reviews as well as short communications are welcome. Research areas may include (but are not limited to) the following: liquid chromatography applied to analytical methods for drugs determination in biological matrices or pharmaceutical formulations, forensic and toxicological analysis, residue analysis, sample preparation, and development and validation of new analytical methods.

We look forward to receiving your contributions.

Dr. Maria Nieddu
Dr. Elena Baralla
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Separations is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.