Advanced Biosensors for Human Disease Detection and Monitoring

Dear colleagues,

Innovative technology such as sensors and biosensors would represent a powerful tool in clinical applications for identifying health and/or pathological status and monitoring changes during the subject life and activities. Early detection plays a crucial role in treatment planning and prognostic evaluation. An early assessment of the pathological status of a patient, tracing of disease progression, and monitoring of therapy efficacy are primary objectives in healthcare research. In this respect, biosensors are very promising tools for disease diagnosis as well as for monitoring stable status or acute relapses due to biomarker detection. Compared to traditional approaches, such as immunochemical methods or analytical techniques, biosensors’ main advantages are represented by their ease of use, reduced cost, portability, and possibility of online monitoring of biomarkers by in situ measurements mainly due to their integration into lab-on-chip (LoC) and point-of-care (PoC) devices, as well as the their use with fragile people (e.g., newborns, elderly, disabled people) or in extreme conditions (e.g., space missions). In addition, continuous evolution of micro- and nanobiotechnologies has provided the achievement of that level of sensitivity and accuracy that allows the implementation of biosensors in clinical research in an increasingly targeted way.

This Special Issue invites contributions, as original research articles or reviews, on the current advances in biosensor technology and improvements, especially focused on clinical and environmental monitoring applications, as well as on the improvements reached by biotechnologies, including materials, device design and fabrication, and analytical techniques. Biosensors concerning biological matrices non-invasively sampled will be particularly welcome.

Dr. Maria Giovanna Trivella
Prof. Dr. Abdelhamid Errachid
Dr. Francesca G. Bellagambi
Guest Editors

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