Grand Celebration: 100th Anniversary of the Discovery of Heparin
A special issue of Pharmaceuticals (ISSN 1424-8247).
Deadline for manuscript submissions: closed (31 May 2016) | Viewed by 47918
Special Issue Editors
2. Centro Interdisciplinar de Investigação Marinha e Ambiental (CIIMAR/CIMAR), Universidade do Porto, Edifício do Terminal de Cruzeiros do Porto de Leixões, Av. General Norton de Matos s/n, 4050-208 Matosinhos, Portugal
Interests: medicinal chemistry; organic synthesis; natural products; xanthones; flavonoids; antimicrobials; antitumor; antifouling
Special Issues, Collections and Topics in MDPI journals
2. Laboratory of Organic and Pharmaceutical Chemistry, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal
Interests: medicinal chemistry; organic synthesis; heterocycles; P-glycoprotein; anticancer; antimicrobials; chiral drugs; marine natural products
Special Issues, Collections and Topics in MDPI journals
2. CIIMAR | Interdisciplinary Centre of Marine and Environmental Research, University of Porto, Novo Edifício do Terminal de Cruzeiros do Porto de Leixões, Avenida General Norton de Matos, s/n, 4450-208 Matosinhos, Portugal
Interests: medicinal chemistry; synthesis of sulfated and glycosylated small-molecule mimetics of heparin; discovery of biological activities for persulfated versus partially sulfated small molecules; antifouling studies of partially sulfated small molecules; antithrombotic studies of persulfated small molecules; structure–activity and structure–property relationship studies of bioactive small molecules
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Heparin has been used clinically as an antithrombotic agent since the 1940s. However, the history of heparin began in 1916, during the World War I. Continued work on structural characterization, synthesis, structure-activity relationship of heparins has expanded their activity/function spectrum and opens new potential applications. To celebrate a century of discoveries and progresses on this field, the journal Pharmaceuticals now invites valuable contributions that report original observations or reviews. Select topics are listed below and you are welcome to generate a unique topic. This collection of manuscripts will be published as a Special Issue in the journal first and hopefully as an eBook later on. Investigators in the Glycosaminoglycans or other related fields are encouraged to participate in this special event. Please email Prof. Madalena Pinto ([email protected]; [email protected]) if you would like to make a contribution.
- New heparin mimetics
- New therapeutic applications for heparin/heparan sulfate
- Improved preparation and synthesis of heparins
- Structural characterization of heparin, low molecular weight heparins (LMWHs), and heparin oligosaccharides
- Structure-activity relationships of heparin, LMWHs and heparin oligosaccharides for inflammation, cancer and anticoagulant activities
- Improving oral bioavailability of heparins
Prof. Dr. Madalena M. M. Pinto
Dr. Maria Emília de Sousa
Dr. Marta Correia da Silva
Guest Editors
Manuscript Submission Information
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Keywords
- heparin
- glycosaminoglycans
- synthesis
- structural characterization
- anticoagulant
- bioavailability
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Related Special Issue
- Glycosaminoglycans and Proteoglycans in Pharmaceuticals (11 articles)