Special Issue "Pharmacokinetics and Pharmacodynamics of Psychoactive Substances: Clinical and Forensic Aspects 2023"

A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Pharmacology".

Deadline for manuscript submissions: 30 August 2023 | Viewed by 210

Special Issue Editor

1. TOXRUN – Toxicology Research Unit, University Institute of Health Sciences, Advanced Polytechnic and University Cooperative (CESPU), CRL, 4585-116 Gandra, Portugal
2. Department of Public Health and Forensic Sciences, and Medical Education, Faculty of Medicine, University of Porto, 4200-319 Porto, Portugal
3. UCIBIO-REQUIMTE, Laboratory of Toxicology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal
4. MTG Research and Development Lab, 4200-604 Porto, Portugal
Interests: real-world evidence; implementation science; toxicology; forensic sciences; psychoactive substances; drugs; biomedical research; scientometrics; scientific medical writing; pedagogical Innovation
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue aims to cover the chemical structure, available products, pharmacokinetics, pharmacodynamics, metabolomics, clinical manifestations, diagnostics, and treatment of acute intoxications related to psychoactive substances in order to highlight their impact on public health. To better understand the clinical and forensic effects, pharmacokinetics should be explored to find active and inactive metabolites and other biomarkers. Indeed, polymorphisms in genes encoding enzymes (e.g., CPY2B6) involved in metabolism or target receptors may influence both drug efficacy and toxicity. Besides genetics, the extensive metabolism by P450 can lead to important interactions when drugs are taken concomitantly. The identification of additional metabolites is also needed during drug development and for clinical and forensic toxicology, where specific metabolites are used to confirm xenobiotic exposure as potential biomarkers.

Prof. Dr. Ricardo Jorge Dinis-Oliveira
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceuticals is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • psychoactive substances
  • toxicokinetics
  • toxicodynamics
  • toxicological analysis
  • interpretation of toxicological reports
  • antemortem toxicology
  • postmortem toxicology
  • clinical and forensic issues

Published Papers

This special issue is now open for submission.
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