Special Issue "Recent Advances on Acoustic, Ultrasonic, and Magnetic Drug Delivery"

A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Pharmaceutical Technology".

Deadline for manuscript submissions: 15 September 2022 | Viewed by 297

Special Issue Editor

Dr. Oveis Pourmehran
E-Mail Website
Guest Editor
Adelaide Medical School, The University of Adelaide, North Terrace, Adelaide, SA 5005, Australia
Interests: acoustic drug delivery; magnetic drug delivery; Computational Fluid Dynamics (CFD); biomechanics; rhinology

Special Issue Information

Dear Colleagues,

Using an active targeting drug delivery approach, the efficiency of drug delivery can be significantly increased when compared with the passive approach. Acoustic and magnetic drug delivery techniques are two novel active drug delivery approaches. The use of acoustics in biomedical practices has been expanded from diagnostic applications to non-invasive drug delivery. The use of acoustics in drug delivery procedures can be divided into two categories: ultrasonic-enhanced drug delivery (known as high-intensity focused ultrasound (HIFU)) and low-frequency acoustic drug delivery (ADD). In the former, the acoustic frequency (f) that is used for drug delivery falls in the spectrum of f > 20 kHz, which is beyond the threshold of human hearing. In the latter drug delivery method (i.e., ADD), the low frequencies refer to frequencies below 20 kHz, which can be sensed by the human ear. The use of transcutaneous ultrasound for therapeutic purposes has been shown to be a promising active targeting approach when used for internal treatment or in the blood circulation system. On the other hand, a low-frequency acoustic field has recently been demonstrated to be advantageous in nasal drug delivery, especially for drug delivery to the paranasal sinuses. Studies have demonstrated that low-frequency drug delivery to the paranasal sinuses can enhance drug deposition in the sinuses significantly.

Since 1970s, when microparticles coated with polymer were first developed, magnetic drug targeting (MDT) using drug-loaded microparticles attracted great attention from many researchers seeking to elaborate on drug delivery options to targeted sites. In MDT, an external magnetic field manipulates the magnetic drug carriers to deliver a drug to targeted locations in the body and retains them there, which can reduce the adverse side effect and improve the drug delivery efficiency significantly. MDT can also be used to kill the tumour and cancer cells in a different way: magnetic microparticles are injected into the body and then an electromagnetic field is applied externally to increase the temperature of the particles, using hysteresis loss, to destroy the tumour/cancer.

The journal Pharmaceuticals invites both reviews and original articles that shed light on the challenges and opportunities of using the magnetic field, acoustic wave, and pulsating flow in drug delivery enhancement as well as in the diagnosis of various diseases. Topics include but are not limited to: Targeted Drug delivery, Acoustic Drug Delivery, Magnetic drug targeting, Pulsating Flow, high-intensity focused ultrasound (HIFU), Acoustic Rhinometry, Chemotherapy, Hyperthermia, Chemopotentiation, Ultrasonography, Cavitation, Lung Drug Delivery, Nasal Drug Delivery, Computational Fluid Dynamics, Finite Element Analysis, Biomechanics of Human Airways, Chronic Rhinosinusitis. The collection of manuscripts will be published as a Special Issue of the journal.

Dr. Oveis Pourmehran
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceuticals is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • ultrasound
  • acoustic drug delivery
  • magnetic drug delivery
  • acoustic rhinometry
  • computational fluid dynamics (CFD)

Published Papers

This special issue is now open for submission.
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