Advances in Drug Analysis and Drug Development

Dear Colleagues,

The different phases of drug development include preclinical and clinical drug development. During this long-term process, a large number of different compounds (active pharmaceutical substances, excipients, impurities and metabolites) are monitored, and the development of new analytical methods facilitates the implementation.

This Special Issue of Pharmaceuticals will be a collection of research articles, short communications and reviews related to original and novel analytical methods developed for the evaluation of active substances in various dosage forms during drug development.

From the analytical point of view, a special challenge is the identification and determination of metabolites, as the products of drug metabolism, and other endogenous compounds. Green and sustainable analytical procedures are more than welcome, as well as methods, including the pre-treatment of different dosage forms and biological materials as samples.

The coverage of this Special Issue includes, but is not limited to:

• Advances in instrumental analysis in drug development;
• Preformulation and pharmaceutical formulation studies;
• Preclinical and clinical evaluation of formulation technologies;
• The pharmacokinetic analysis of active substances and metabolites;
• Innovative processing and analytical technologies;
• Extractable and leachable testing in pharmaceutical analysis;
• Bioanalysis of nano-drug delivery systems;
• Lab-on-chip technology;
• High-throughput screening in preformulation studies;
• Validation and regulatory aspects in pharmaceutical analysis.

We are looking forward to hearing from you.

Dr. Daniela Amidžić Klarić
Prof. Dr. Ana Mornar
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceuticals is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• analytical methodology

• chromatographic techniques
• spectrometric techniques
• thermal analysis techniques
• sample preparation
• drug stability
• compatibility study
• bioavailability studies
• therapeutic drug monitoring
• quality by design in pharmaceutical analysis