Immunity and Immunoregulation in Helminth Infections
A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Immunological Responses and Immune Defense Mechanisms".
Deadline for manuscript submissions: 31 August 2025 | Viewed by 638
Special Issue Editor
Interests: immunoregulation in parasitic diseases; helminths; dendritic cell; macrophage’s response to inflammatory stimulus; interactions between helminths and their molecules with the host; inflammatory-mediated diseases
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Helminth infections are a major public health problem worldwide. They are deeply rooted in human evolution and will prevail for many years to come. They can disseminate in their host in almost any tissue, from muscle to brain. Thus, it is critical to not forget about the damage they cause to the people suffering from these infections. The only way to eradicate or control such helminth infections is to increase our knowledge of them: studies on host immunity can deepen our understanding of the pathogenesis of helminth infections. On the other hand, capacities that many helminth parasites have to regulate the immune response of their hosts to remain inside them for long periods, sometimes without causing any symptoms, are well-established. This immune silence needs to be broken to generate immunity. Therefore, if we know these helminth–immunoregulatory mechanisms, we could develop vaccines against them or take advantage of such activities to modulate unwanted exacerbated immune responses.
Therefore, the goal of this Special Issue is to put together the recent findings achieved, despite the pandemic, by researchers interested in helminth infections.
This Special Issue invites either original research or review articles focused on, but not limited to, the following “hot topics” in parasitic helminths research:
- Immunomodulation on parasitic helminth diseases;
- Immunity to helminths;
- Cytokines/chemokines and susceptibility or resistance to helminth infections
- Co-infections;
- Co-morbidities during parasitic helminth infections;
- Signaling pathways and susceptibility to helminths;
- Role of innate lymphoid cells (ILCs) in helminth immunity;
- Vaccine development against helminth
Dr. Luis I. Terrazas
Guest Editor
Manuscript Submission Information
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Keywords
- helminths
- cytokines
- signaling pathways
- co-infections
- infections and co-morbidities
- immunity
- immunomodulation
- immune checkpoints
- pathogenesis
- vaccines
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