Special Issue "Nutrition for Eye Health"
Deadline for manuscript submissions: closed (31 August 2020) | Viewed by 33129
Interests: animal models; ocular diseases; retinal function; neurodegeneration; neuroprotection; angiogenesis; inflammation; anti-angiogenic and anti-inflammatory compounds; dietary supplementation; eye health
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Among ocular diseases, those that substantially affect the vision by disrupting the functioning of retinal neurons represent a major burden with a high social and economic impact. In particular, visual impairment exacts an enormous financial and social cost on developing countries, thus requiring much research work into the cause and prevention of major blinding diseases. In addition to pharmacological therapies, the management of ocular pathologies includes nutritional supplements such as antioxidants, vitamins or fatty acids that are at present extensively investigated in terms of prophylactic benefits, potential harm, and optimal use. For instance, naturally occurring substances that humans take in with a normal diet can serve as antioxidants and free radical scavengers, possibly reducing or eliminating tissue damage from oxidation or the presence of free radicals in those tissues. However, evidence for the benefit of diet supplementation is often controversial. For instance, epidemiological studies have indicated potential preventive effects of omega-3 fatty acids against dry AMD, although the results of the Age-Related Disease Study 2 (AREDS2) seem to exclude their potential in preventing AMD progression. An additional complication in the use of nutraceuticals as therapeutic strategies is their scarce oral bioavailability, thus rendering investigations aimed to improve this aspect of fundamental importance.
This Special Issue collects reviews or original papers representing the state of the art on nutrition and eye health in terms of clinically relevant animal models through which to understand the mechanisms underlying the efficacy of diet supplementation. In addition to preclinical studies, attempts to give an overview of the clinical investigation of dietary supplementation as a potential treatment for ocular pathologies are also recommended.
Prof. Paola Bagnoli
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Animal models of ocular diseases
- Anterior chamber
- Dietary supplementation
- Protective mechanisms