17 September 2026
Bioactive peptides derived from Phaseolus vulgaris represent a promising source for the development of functional ingredients because of the multiple biological activities associated with bean proteins and their hydrolysis products. In this review, a...
Phenolic compounds exhibit important biological properties; however, their solubility affects bioavailability when they are consumed by oral administration. Enzymatic glycosylation of these molecules improves solubility and bioavailability; however,...
Food and nutrition insecurities remain major challenges in rural communities, highlighting the need to identify affordable and nutrient-dense indigenous food resources. Therefore, this study evaluated the nutritional composition, antioxidant activity...
The authors would like to make the following correction to their published paper [...]
Ellagitannins (ETs) derived from rambutan (Nephelium lappaceum L.) peel are polyphenols that have gained prominence in the food and nutraceutical industries due to their high bioactivity. The objective of this study was to evaluate the encapsulation...
Natural polyphenols have gained increasing attention as potential anticancer agents, although the selective effects of many plant-derived extracts on cervical cancer cells remain insufficiently characterized. Rambutan (Nephelium lappaceum) peel, an u...
Carbohydrates and their constituent monosaccharides have historically been viewed as metabolic substrates that provide cellular energy. However, recent evidence demonstrates that monosaccharides can also function as bioactive signaling molecules that...
The authors would like to make the following correction to their published paper [...]
Antibiotic-induced dysbiosis can cause persistent alterations in gut microbial composition and fermentative metabolism, yet the long-term role of mushroom β-glucan-based prebiotics in supporting post-antibiotic microbiota modulation remains poor...
Quercetin is a nutraceutical flavonoid whose aqueous use is limited by poor solubility and chemical instability. Existing polysaccharide carriers may require chemical modification, crosslinkers, multicomponent formulations, or complex processing. Her...
The rapid expansion of the global nutraceutical industry has heightened the urgency for rigorous yet efficient safety assessment of food-derived bioactives. Conventional toxicological methods, while indispensable, are often costly, time-consuming, an...
Background: The Mediterranean Diet (MedDiet) is a global benchmark for the prevention of cardiometabolic diseases and healthy aging, with Olea europaea L. (O. europaea L.) and Citrus bergamia Risso et Poiteau (bergamot) serving as primary sources of...
Neuropathic pain is a chronic, difficult-to-treat condition arising from injury or disease of the somatosensory nervous system. Current pharmacological treatments provide limited relief for many patients and are often associated with adverse effects,...
Background/Objectives: Flavonoids are a diverse group of dietary polyphenolic compounds associated with a range of important biological activities. However, their low systemic bioavailability and extensive metabolism raise questions about how they ex...
The authors would like to make the following correction to their published paper [...]
Pediatric sarcopenic obesity (PSO) is an emerging conceptual framework characterized by the coexistence of excess visceral adiposity and impaired skeletal muscle accretion. Evidence suggests that this pathology is driven by systemic meta-inflammation...
Introduction: It is estimated that about 20–35% of the Western population reports symptoms of food intolerances, which is a growing trend. Intolerance to histamine, a dose-dependent, non-allergic food hypersensitivity reaction, despite similar...
Mint (Mentha spp.) teas are widely consumed as functional herbal beverages and represent important dietary sources of bioactive volatile compounds. The present study comparatively evaluated the chemical composition and antimicrobial activity of essen...
Peptic ulcer is a multifactorial and debilitating gastrointestinal disorder affecting about 10 million people worldwide. The effectiveness of many anti-ulcer drugs is often limited by adverse effects, thereby making the need for safer, natural altern...
Adaptogens are substances touted for their ability to promote resilience to stress. With more individuals reporting a greater degree of perceived stress, renewed attention has been focused on novel adaptogen complexes for stress reduction. Salidrosid...
Background: Resistance training increases lean mass, muscle accretion and performance. These adaptations from resistance training can be further increased with 5 g of creatine monohydrate supplementation (CrM). In addition to dose, it has been propos...
The leaves and bark of Litsea species have traditionally been used as folk medicine to treat pain, headache, inflammation, diarrhea, and gastroenteritis. This study investigated whether dietary supplementation with Litsea cubeba leaves could preserve...
Eggplant is a crop of significant global importance. However, strict selection criteria generate large amounts of biomass that contain hydrophilic bioactive compounds. These compounds are associated with the prevention and treatment of diseases such...
Inflammation is an essential biological response that enables host defense, tissue repair, and restoration of homeostasis after injury or infection [...]
In the original publication [...]
Hypertension frequently remains uncontrolled despite pharmacological therapy, supporting interest in complementary nutritional strategies. This narrative review evaluates human clinical evidence and mechanistic pathways for minerals, polyphenols, ome...
Introduction: Vitamin B12 (VB12), particularly its active form methylcobalamin (MeB12), contributes to neuromuscular function and energy metabolism, which may be relevant for sports performance. However, evidence on the acute effects of MeB12 supplem...
Rosehip (the “fruit” of Rosa canina L, commonly known as dog rose) is an emerging functional food, yet native Greek populations remain under-explored. This study screened 76 wild genotypes from Northern Greece for radical scavenging activ...
Pistacia lentiscus L. var. Chia is an endemic tree cultivated in the Southern part of Chios Greek Island. Chios mastiha, the aromatic resin secreted from this tree, has been used as traditional remedy since ancient times to cure many peptic system di...
Hops (Humulus lupulus L.) is a plant species with a multitude of uses in medicine, food science and agriculture. Xanthohumol, the major prenylflavonoid in hop cone extract, possesses anti-cancer activity. Xanthohumol also exhibits strong antimicrobia...
Ecdysterone is a natural compound proposed as an alternative to anabolic-androgenic steroids (AAS) due to its comparable ergogenic potential and more favorable safety profile. This narrative review summarizes current evidence using a standardized sea...
Tyrosol, a phenolic compound derived from olive products, exhibits anti-inflammatory, neuroprotective, and cardiometabolic properties, whereas creatine is a well-established ergogenic aid with documented benefits for muscular performance and emerging...
Cardiovascular diseases (CVDs) remain the leading cause of morbidity and mortality worldwide. Despite their often-asymptomatic progression and complex therapeutic management, a substantial proportion of CVDs is preventable through early intervention...
Oilseed consumption in Morocco has seen enhanced relevance due to its nutrient and functional value. This research paper was undertaken to establish the most consumed oilseeds in the country and to compare their chemical profiles, nutritional content...
In the original publication, there was a mistake in Figure 12 as published [...]
Silymarin (Silybum marianum (L.) Gaertn. extract) is a widely used botanical for liver disease, yet clinical results remain inconsistent. Most mechanistic work uses supraphysiological aglycones, whereas humans are exposed predominantly to phase II co...
In this study, the pharmacokinetic (PK) characteristics of oleuropein present in the olive tree (Olea europaea) were determined. We developed and validated a highly sensitive ultra-performance liquid chromatography coupled with tandem mass spectromet...
Roselle beverage residue (RBR), a by-product of Hibiscus sabdariffa L. processing, retains bioactive compounds, including soluble and insoluble dietary fiber and polyphenols. Its antihyperglycemic effect in type 2 diabetes mellitus (T2DM) has been pr...
This study aimed to explore the efficacy of oral supplementation with 11 probiotic strains, combined in the strain mix Probatech™ (Centro Sperimentale del Latte S.r.l Strada Provinciale per Merlino, 326839 Zelo Buon Persico (LO), Italy) and del...
Natural by-products (NBPs), including pomace, peels, stems, and skins, account for over 50% of materials generated during fresh fruit processing. Most of these are discarded or landfilled, contributing to environmental pollution. NBPs are rich in bio...
There was an error in the original publication [...]
Oxidative stress and environmental factors impair spermatogenesis and testicular function. The gut–testis axis has emerged as an important regulator of male reproductive health, influencing spermatogenesis beyond traditional endocrine control....
Dietary fiber (DF) has a profound influence on human health mainly by modulating the gut microbiota. This review provides an overview of DF derived from cereals, legumes, fruits, vegetables, fungi, and seaweeds, specifically addressing the relationsh...
Chrysanthemum indicum L. (C. indicum), a perennial herb widely distributed across East Asia, has long been utilised in traditional medicine and as a functional food ingredient. Contemporary research has revealed a chemically diverse phytochemical pro...
The authors would like to make the following correction to their published paper [...]
Recent advances in chiral analytical chemistry have revealed that fermented and natural foods contain substantial amounts of D-amino acids (D-AAs), the mirror-image counterparts of L-amino acids, leading to their recognition as nutraceutical componen...
Estrogen suppress food intake, and soy isoflavones exhibit estrogen-like activities. However, the specific isoflavone components responsible for appetite regulation and their underlying neuroendocrine mechanisms remain unclear. We investigated whethe...
The authors would like to make the following correction to their published paper [...]
