Nanoparticulate Platforms for Enhancing Immunotherapy

Dear Colleagues,

Immunotherapy approaches either stimulate or suppress the immune system during pathological conditions for the benefits of recipients. Recently, different immunotherapy-based nanoparticulate platforms have received significant attention for the treatment of various diseases, including cancers, autoimmune disorders, infections, and tissue or organ transplantation related rejections. Undoubtedly, nanoparticle-based immunotherapies have shown promising therapeutic outcomes in both preclinical and clinical studies.

Various types of nanoparticles have been developed to improve cancer treatment outcomes by targeting different immunological cascades to boost the immune reaction, and they have been proved to exert minimal side effects compared to conventional therapies. In infectious diseases, nanoparticles can be used to activate cellular and humoral immunity to help the body to fight against infections. In autoimmunity and transplantation settings, the immunomodulatory nanoparticles can suppress immunity and induce antigen-specific tolerance to the grafts, and thus have a great potential to abrogate the life-threatening adverse effects associated with the conventional immunosuppressive agents.

The current Special Issue invites all types of articles on nanoparticle-based approaches for immunotherapy, particularly focused on but not limited to cancer immunotherapy, autoimmune diseases, infections, and transplantation. We welcome any original articles, review papers, and communications dealing with the use of nanoparticles for immunotherapy.

Dr. Shiva Pathak
Dr. Shobha Regmi
Dr. Biki Gupta
Guest Editors

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