Special Issue "Design of Micro- and Nanoparticles: Self-Assembly and Application"
Deadline for manuscript submissions: 31 March 2021.
Interests: silica nanoparticles; surface modification; multifunctional nanoparticles and colloids; self-assembled organic nanoparticles; oligolactic and polylactic acid nanomaterials; organic and hybrid organic–inorganic nanosized materials; supramolecular polymers; biosensors
Micro/nanoparticles (M&NPs) have attracted researchers’ interest due to their unique chemical and physical properties. Recent advances in the synthesis of M&NPs (metallic, metal oxide, silica, polymeric, lipid-based, supramolecular, colloidal, and carbon-based M&NPs) have offered exciting opportunities for many applications, such as catalysis, plasmonics, sensors, magnetism, drug delivery, and nanomedicine. The use of self-assembly for the synthesis or modification of M&NPs provides unlimited possibilities for designing nanomaterials with desired properties.
This Special Issue of Nanomaterials “Design of Micro- and Nanoparticles: Self-Assembly and Application”, aims at collecting articles or reviews that highlight synthesis, modification, properties, and applications in various areas related to M&NPs. We would like to invite scientists of diverse backgrounds (material science, organic and inorganic chemistry, biochemistry, and biology) to contribute their works to this Special Issue.
Potential topics include but are not limited to the following topics:
- The synthesis and application of micro/nanoparticles based on self-assembly
- Micro/nanoparticles surface functionalization
- Micro/nanoparticles interaction with biomolecules
- Design of novel hybrid organic-inorganic micro/nanoparticles
- The role of micro/nanoparticles in molecular recognition
- The studies of the biological activity and toxicity of micro/nanoparticles
Prof. Dr. Ivan Stoikov
Dr. Pavel Padnya
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nanomaterials is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Plasmonic nanoparticles
- Molecular recognition
- Bio applications
- Optical property
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
Title: Electrochemical DNA sensor based on copolymer of proflavine and Azure B for doxorubicin determination
Authors: A. Porfireva1; G. Evtugyn1,2
Affiliation: 1 Chemistry Institute of Kazan Federal University; 2 Chemical Technology Institute of Ural Federal University
Abstract: Electrochemical polymerization has been applied for the assembling of the thin redox active film onto the glassy carbon electrode. The formation of the films was confirmed by scanning electron microscopy and electrochemical impedance spectroscopy. The voltammograms showed reversible transfer of one electron with the pH depending rate constant. The resulting coating was compared with polyproflavine and poly(Azure B) in order to establish the stoichiometry of redox stages and contribution of certain monomers in the electrochemical behavior of the products. The electrode covered with the copolymer was applied for electrostatic assembling of the nano-sized DNA aggregates accumulated in open circuit mode on its surface. The close contact of the DNA nanoaggregates and underlying film made it possible to detect weak specific interactions with DNA. As an example, intercalation of the native DNA with anthracycline preparation, Doxorubicin, was monitored using cyclic voltammetry and electrochemical impedance spectroscopy. The limit of detection below 0.1 nM has been obtained and possibility for direct monitoring of blood serum and urine was shown using artificial spiked samples
Title: Magnetic nanoparticles for data storage
Authors: Tomasz Blachowicz, Andrea Ehrmann
Affiliation: Bielefeld University of Applied Sciences, Minden, Germany
Abstract: Recent lithographic methods allow for preparing fine structures with a resolution far below 100 nm. Magnetic nanostructures can be used to store data, applying new concepts, such as the Racetrack memory, but also using special materials enabling skyrmion formation, special shapes to prepare quaternary storage devices which allow for storing two or even more bits per storage position, etc. Here we give an overview of recent development in the field of magnetic nanoparticles for data storage.
Title: Antiviral Potential of Nanoparticles: Can nanoparticles fight against coronaviruses?
Authors: Sangiliyandi Gurunathan
Affiliation: Konkuk University, Seoul, South Korea
Abstract: Infectious diseases account for more than 20% of global mortality, and viruses are responsible for about one third of these deaths. Viral infections have recently emerged COVID-19 is not only as a health threat to people but it is very serious issues to death. It causes more than 81 million people are infected and hundreds of thousands of people were died. Coronaviruses, such as severe acute respiratory syndrome (SARS), middle east respiratory syndrome coronavirus (MERS); severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), have endangered human life, and especially the COVID-19 caused by SARS-CoV-2 outbreak not only dangerous to public health globally with enormous deaths and eventually leads to great economic loss. Hence, it is necessary to speed up the development of antiviral drug and/or vaccine that would help mitigate this pandemic. In this regard, nanoparticles can be used as antiviral agents for the treatment of variety of viral infections. The use of nanoparticles provides an interesting opportunity for the development of novel antiviral therapies with lower possibility to develop drug resistance as compared to conventional chemical based antivirals therapy. The present focuses on various aspects includes mechanism of entry of viruses into the host cells, use of major and important type of nanomaterials such as silver, gold, quantum dots, organic nanoparticles, lysosomes, dendrimers and polymers against various type of viral infections. Further we discussed antiviral mechanism, therapeutic approaches of nanoparticles and impact of nanoparticles on coronaviruses. Finally, we provide a conclusion and future perspective of nanoparticles.
Title: Heparin/Protamine Particle-Based Self-Assembling Protein as a Novel Protein Carrier In Vitro and In Vivo
Authors: Shingo Nakamura 1, Naoko Ando 1, Masayuki Ishihara 1, and Masahiro Sato 2
Affiliation: 1 Division of Biomedical Engineering, National Defense Medical College Research Institute, Saitama 359-8513, Japan, 2 Section of Gene Expression Regulation, Frontier Science Research Center, Kagoshima University, Kagoshima 890-8544, Japan.
Abstract: We previously reported that heparin/protamine particles (LHPPs), produced as nanoparticles through simple mixing of raw materials, exhibit protein-sustained release and have the ability to retain cells. In the present study, we modified LHPPs without employing any organic synthetic approach. The resulting LHPPs are re-named as improved LHPPs (i-LHPPs) and have the ability to retain cell-penetrating peptides based on electrostatic interactions. We examined whether i-LHPPs are able to introduce exogenous protein (i.e., lacZ protein encoding bacterial beta-galactosidase) into cultured cells in vitro, or into murine hepatocytes in vivo through intravenous injection of mice. We found accumulation of the transferred protein in both in vitro cultured cells and hepatocytes in vivo. To our knowledge, successful delivery towards hepatocytes in vivo is a few. The present i-LHPPs-based protein delivery technique will be useful for in vivo functional modification of mouse hepatocytes using Cas9 protein-mediated genome editing targeted to a specific gene, leading to creation of hepatic disease animal models or research aimed to treat hepatic diseases.