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Molecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Recent Advances on Biomass Conversion and CO2 Valorization: Steeping Towards a Circular Economy, 2nd Edition
edited by and Eva Castillejos-Lopéz
submission deadline 31 Jan 2027 | 1 articles | Viewed by 1530 | Submission Open
Keywords: CO2 valorization; biomass conversion; catalysis
(This special issue belongs to the Section Green Chemistry)
Natural Products Chemistry in the Americas
edited by Margarete Zanardo Gomes, and
submission deadline 31 Jan 2027 | 3 articles | Viewed by 1505 | Submission Open
Keywords: natural products chemistry; bioactive compounds; extraction techniques; biological applications; biodiversity in the Americas; sustainable bioprospecting; pharmaceutical potential
(This special issue belongs to the Section Natural Products Chemistry)
Essential Oils: Chemical Characterization, Bioactivity and Innovative Applications
edited by and Florin Imbrea
submission deadline 31 Jan 2027 | 2 articles | Viewed by 1394 | Submission Open
Keywords: essential oils; phytochemistry; green extraction technologies; bioactivity; antimicrobial activity; antibiofilm activity; antimicrobial resistance; antioxidant activity; nanoencapsulation; molecular docking; therapeutic potential; alternative medicine; functional foods; food preservation; biopesticides; sustainable agriculture; natural bioactive compounds; novel delivery systems
(This special issue belongs to the Section Natural Products Chemistry)
Chemical and Functional Characterization of Novel Plant Proteins
edited by
submission deadline 31 Jan 2027 | 1 articles | Viewed by 1121 | Submission Open
Keywords: novel plant proteins; chemical characterization; functional properties; protein structure–function relationships; extraction and modification techniques; techno-functional behavior; protein digestibility and bioactivity; sustainable protein sources
(This special issue belongs to the Section Food Chemistry)
Production of Artemisia and Its Pharmacology vs. Artemisinin
edited by and Yuliang Wang
submission deadline 31 Jan 2027 | 1 articles | Viewed by 1049 | Submission Open
Keywords: Artemisia annua; Artemisia afra; synergism; infectious and chronic diseases; phytochemistry; artemisinin biosynthesis
(This special issue belongs to the Section Natural Products Chemistry)
Microbe Metabolites as Functional and Bioactive Components in Food
edited by
submission deadline 31 Jan 2027 | 1 articles | Viewed by 1046 | Submission Open
Keywords: microbial metabolites; functional food; bioactive compounds; fermentation; gut microbiota; single-cell protein; microbial lipids; natural pigments; probiotics
Advanced Optoelectronic Functional Materials: From Fundamental Innovation to Cutting-Edge Applications
edited by Fuquan Bai
submission deadline 31 Jan 2027 | 1 articles | Viewed by 943 | Submission Open
Keywords: design; synthesis; characterization; application; theoretical; optoelectronic functional material; perovskite solar cell; 2D material; graphene; TMDs; heterostructure; photodetector; flexible electronics; sensor; quantum dot; LED
(This special issue belongs to the Section Materials Chemistry)
Advanced Analytical Approaches and Chemical Profiling of Essential Oils: From Composition to Bioactivity
edited by
submission deadline 31 Jan 2027 | 1 articles | Viewed by 922 | Submission Open
Keywords: essential oils; novel analytical approaches; metabolomics; chemometrics; chemical profiling; bioactivity; volatile terpenes; phenylpropanoids
(This special issue belongs to the Section Natural Products Chemistry)
Biochemically Active Natural and Semisynthetic Products: Extraction, Characterization, and Application—2nd Edition submission deadline 31 Jan 2027 | 1 articles | Viewed by 877 | Submission Open
Keywords: natural and semisynthetic products; extraction, isolation, and purification; identification and structural elucidation; biological properties; multidisciplinary applications
(This special issue belongs to the Section Natural Products Chemistry)
Molecular Design and Synthesis of Novel Energetic Compounds, 2nd Edition
edited by
submission deadline 31 Jan 2027 | 1 articles | Viewed by 842 | Submission Open
Keywords: energetic compounds; molecular design; synthesis; structure; performance; sensitivity
Bioactive Compounds in Terrestrial and Aquatic Plants: Emerging Therapeutic Applications in Human Health and Disease Management submission deadline 31 Jan 2027 | 1 articles | Viewed by 840 | Submission Open
Keywords: plant-derived bioactive compounds; natural product-derived therapeutics; phytochemicals and biological activity; marine algae bioactive compounds; plant primary and secondary metabolites; extraction and isolation techniques; antioxidant activity; anti-inflammatory properties; immunomodulatory effects; plant therapeutic potential; biomedical applications of plant extracts; cosmeceuticals and nutraceuticals from natural sources
(This special issue belongs to the Section Natural Products Chemistry)
Design and Applications of Phase Change Materials for Energy Storage and Conversion
edited by and Yinsheng Yu
submission deadline 31 Jan 2027 | 1 articles | Viewed by 747 | Submission Open
Keywords: phase change materials; materials chemistry; energy conversion and storage; thermally conductive composites; microencapsulation and interfacial engineering
(This special issue belongs to the Section Materials Chemistry)
Advanced Manufacturing and Interface Engineering for Perovskite Materials
edited by Chaoyu Xiang
submission deadline 31 Jan 2027 | 1 articles | Viewed by 705 | Submission Open
Keywords: metal halide perovskite; photovoltaics; LED; detectors and sensors
(This special issue belongs to the Section Materials Chemistry)
Advanced Chemical Analysis, Molecular Interactions and Remediation Strategies for Micro- and Nanoplastics
edited by Asli Baysal and
submission deadline 31 Jan 2027 | 1 articles | Viewed by 661 | Submission Open
Keywords: microplastics; nanoplastics; advanced chemical analysis; molecular interactions; polymer degradation; contaminant adsorption; remediation technologies; advanced oxidation processes; plastic additive leaching
Analysis and Application of Bioactive Compounds in Functional Foods submission deadline 31 Jan 2027 | 1 articles | Viewed by 655 | Submission Open
Keywords: nutritional bioactive compounds; non-nutritional bioactive compounds; functional foods development; food supplement; green extraction approach; new analytical methods; bioaccessibility; bioavailability
(This special issue belongs to the Section Food Chemistry)
Advances in Micro/Nanomaterials for Catalysis
edited by Juzhe Liu
submission deadline 31 Jan 2027 | 1 articles | Viewed by 652 | Submission Open
Keywords: micro/nanomaterials; catalysis; diverse applications; enhanced performance; advances
(This special issue belongs to the Section Materials Chemistry)
Biotechnological Synthesis, Molecular Characterization, and Formulation of Next-Generation Cosmetic Actives
edited by , Andreea Loredana Vonica-Tincu and Daniela Lucia Muntean
submission deadline 31 Jan 2027 | 1 articles | Viewed by 622 | Submission Open
Keywords: biocosmetics; next-generation cosmeceuticals; microbial fermentation; skin delivery systems; green formulation chemistry; bioactive peptides; sustainable ingredients; encapsulation
(This special issue belongs to the Section Applied Chemistry)
Nutritional and Bioactive Components of Edible Parts of Medicinal Plants2nd Edition
edited by , Joanna Milala and
submission deadline 31 Jan 2027 | 1 articles | Viewed by 584 | Submission Open
Keywords: dietary fiber; polyphenols; ellagitannins; antioxidants; anticancer; minerals; gastrointestinal track; vitamins; phycomponents
(This special issue belongs to the Section Food Chemistry)
Innovations in Heterocyclic Chemistry: Synthesis, Characterization and Bioactivity
edited by Fernanda da Costa Santos Boechat, Maria Cecília B. V. De Souza, and
submission deadline 31 Jan 2027 | Viewed by 582 | Submission Open
Keywords: heterocycles; synthesis; bioactivity; medicinal chemistry; structure-activity relationship (SAR); green chemistry; biochromatography; sustainability
(This special issue belongs to the Section Medicinal Chemistry)
Bioactive Compounds and Antioxidant Activity of Extracts from Natural Plants, 3rd Edition submission deadline 31 Jan 2027 | 1 articles | Viewed by 578 | Submission Open
Keywords: bioactive compounds; natural plant products; antioxidant activity; extraction methods; polyphenols; flavonoids
(This special issue belongs to the Section Natural Products Chemistry)
Research on 1,8-Naphthalimide Scaffold: Present and Future
edited by
submission deadline 31 Jan 2027 | 1 articles | Viewed by 563 | Submission Open
Keywords: 1,8-naphthalimide; derivative of 1,8-naphthalimide; synthesis of 1,8-naphthalimide; spectroscopic properties of 1,8-naphthalimide; fluorescent sensors; biosensors; sensing mechanisms; photophysical properties; crystal structures, computation, fluorescent dyes, cell imaging, textile dyes; OLEDs; electroluminescent materials; liquid crystal displays; ligand; intercalators; biomedical applications (analgesics); anti-depressants; anti-tumor agents; antiprotozoals; antirheumatics; antimicrobials; antivirals; anti-inflammatory agents; enzyme inhibitors
(This special issue belongs to the Section Organic Chemistry)
Advanced Catalysts for Environmental Pollutant Degradation and Remediation
edited by
submission deadline 31 Jan 2027 | 1 articles | Viewed by 530 | Submission Open
Keywords: environmental pollutants; catalytic degradation; environmental remediation; catalytic materials; photocatalysis; advanced oxidation processes
(This special issue belongs to the Section Green Chemistry)
Organosulfur Compounds
edited by
submission deadline 31 Jan 2027 | 1 articles | Viewed by 509 | Submission Open
Keywords: organosulfur compounds; sulfur chemistry; asymmetric synthesis; stereoselective transformations; sulfur-containing heterocycles; catalytic sulfur functionalization; green synthesis; medicinal chemistry; biologically active sulfur compounds; sulfur-based reagents; organic synthesis; sustainable chemistry
(This special issue belongs to the Section Organic Chemistry)
Studies in Polymer Degradation
edited by , Edcleide Maria Araujo and Bastos Y. M. De Almeida
submission deadline 31 Jan 2027 | Viewed by 477 | Submission Open
Keywords: degradation mechanisms; photooxidation; thermal degradation; upcycling technologies and additivities
(This special issue belongs to the Section Macromolecular Chemistry)
Synthesis and Application of Heteroatomic Containing Compounds
edited by
submission deadline 31 Jan 2027 | Viewed by 467 | Submission Open
Keywords: organometallic syntheses; heteroatomic asymmetry center; P-stereogenic center; asymmetric syntheses; enantioselective syntheses; transition metal complexes
(This special issue belongs to the Section Applied Chemistry)
Biochar in Environmental Chemistry: Mechanisms, Reactivity, and Applications submission deadline 31 Jan 2027 | 1 articles | Viewed by 452 | Submission Open
Keywords: biochar; environmental chemistry; sorption mechanisms; reactivity; pollutant transformation; advanced oxidation processes; carbon sequestration; soil remediation; water treatment
(This special issue belongs to the Section Green Chemistry)
Terpene and Phenol-Rich Natural Products: Extraction, Characterization and Biological Evaluation
edited by Sanja Matić and
submission deadline 31 Jan 2027 | Viewed by 443 | Submission Open
Keywords: terpenes; phenolic compounds; natural products; extraction techniques; structural characterization; biological activity; structure–activity relationships
(This special issue belongs to the Section Natural Products Chemistry)
Synthesis, Mechanism and Applications of Fluorinated Compounds
edited by
submission deadline 31 Jan 2027 | 1 articles | Viewed by 430 | Submission Open
Keywords: green chemistry; heterocycles; organofluorides; PFAS; per- and polyfluoroalkyl substances
(This special issue belongs to the Section Organic Chemistry)
Role of High Hydrophobicity in Engineering Biomedical Coating/Surfaces: From Design to Application submission deadline 31 Jan 2027 | Viewed by 410 | Submission Open
Keywords: superhydrophobic surfaces; surface chemistry; molecular design; polymer coatings; biointerface engineering; antibacterial and anti-biofouling; green synthesis; multifunctional materials
(This special issue belongs to the Section Materials Chemistry)
Carbon-Based Electrochemical Materials: Advances and Applications
edited by
submission deadline 31 Jan 2027 | 1 articles | Viewed by 404 | Submission Open
Keywords: electrocatalysis; nanomaterials; HER; OER; ORR; CO2 reduction; fuel cells; single-atom catalysts; MXenes; nanostructured catalysts; sustainable energy; electrochemical conversion
(This special issue belongs to the Section Electrochemistry)
Bioactive Compounds in Plants: Extraction and Application, 2nd Edition submission deadline 31 Jan 2027 | 1 articles | Viewed by 403 | Submission Open
Keywords: bioactive molecules; sustainable extraction; isolation and elucidation; biological activities; mechanisms of action; food science; nanotechnology; delivery systems; bioavailability; controlled release
(This special issue belongs to the Section Natural Products Chemistry)
Innovations in Mass Spectrometry for Analytical Chemistry
edited by Claudia S. Maier and Stanislau Stanisheuski
submission deadline 31 Jan 2027 | Viewed by 379 | Submission Open
Keywords: novel ionization techniques and ion sources; advances in mass analyzers and detectors; integration with chromatographic/electrophoretic separations; ion-mobility and other types of gas-phase separations; novel targeted and untargeted data acquisition strategies; single-cell and spatial MS; functional omics; innovations in data analysis, algorithm development, statistics, and bioinformatics
(This special issue belongs to the Section Analytical Chemistry)
Natural Products as Enzyme Inhibitors: Chemical Characterization and Bioactivity
edited by Niko Radulović and
submission deadline 31 Jan 2027 | Viewed by 377 | Submission Open
Keywords: natural products; enzyme inhibitors; chemical characterization; GC-MS; enzyme kinetics; molecular docking; QSAR; structure-activity relationships
(This special issue belongs to the Section Natural Products Chemistry)
Flavors and Fragrances in China
edited by
submission deadline 31 Jan 2027 | Viewed by 360 | Submission Open
Keywords: Chinese foods; flavor chemistry; flavor analysis; GC–MS/olfactometry; Chinese baijiu
(This special issue belongs to the Section Flavours and Fragrances)
Emerging Organic Contaminants: Advances in Detection and Removal Strategies
edited by Guodong Cao and
submission deadline 31 Jan 2027 | Viewed by 348 | Submission Open
Keywords: emerging organic contaminants; instrumental analysis; occurrence and fate; removal technologies; remediation
(This special issue belongs to the Section Applied Chemistry)
Environmental Analysis and Removal of Emerging Pollutants
edited by , and
submission deadline 31 Jan 2027 | Viewed by 333 | Submission Open
Keywords: pharmaceutical pollutants; industrial additives pollutants; analytical approaches; adsorption and photocatalytic removal processes; redox-driven degradation; bioremediation mechanisms
(This special issue belongs to the Section Green Chemistry)
Precise Design and Action Mechanism of Photocatalytic Nanomaterials
edited by
submission deadline 31 Jan 2027 | Viewed by 321 | Submission Open
Keywords: photocatalytic nanomaterials; precise design; water pollution control; molecular/atomic-level design; structure–activity relationship; microscopic action mechanism; pollution removal performance
(This special issue belongs to the Section Materials Chemistry)
Anti-Cancer and Anti-Inflammatory Activity of Natural Products
edited by
submission deadline 31 Jan 2027 | Viewed by 306 | Submission Open
Keywords: medicinal plant extracts; natural resources; phytochemicals in functional foods; marine natural products natural compounds and human health; analytical methods; novel perspectives on applications of phytochemicals in biomedicine; bioinformatics on bioactive compounds from natural products; structure–activity relationships; ai-driven data mining for research on natural products; biological activities an molecular target identification; natural products for treatment of rare diseases; natural products for mitigating the effects of tobacco smoke; natural products for mitigating the effects of air pollution; natural products for the treatment of cancer; natural products for respiratory diseases; natural products for infectious diseases; natural products against aging; ethnopharmacology; technology transfer of natural products
(This special issue belongs to the Section Natural Products Chemistry)
Exclusive Feature Papers in Analytical Chemistry, 2nd Edition submission deadline 31 Jan 2027 | Viewed by 305 | Submission Open
Keywords: analytical chemistry; instrumentation; environment and food; pharmaceutical industry; green chemistry
(This special issue belongs to the Section Analytical Chemistry)
Circular Bioeconomy Approaches to Natural Products: From Green Extraction to Bioactivity and Biomass Valorization
edited by
submission deadline 31 Jan 2027 | Viewed by 303 | Submission Open
Keywords: natural products; green extraction; bioactivity; by-products; biomass; biomass valorization
(This special issue belongs to the Section Green Chemistry)
Recent Progress in Polymeric Drug Delivery Systems
edited by Barbara Zawidlak-Węgrzyńska, and
submission deadline 31 Jan 2027 | Viewed by 286 | Submission Open
Keywords: biomaterials; biocompatibility of polymer systems; (bio)degradable and synthetic polymers in medical applications; degradation of biomaterials, stimuli-responsive polymers (e.g., pH-, enzyme-, temperature-, or light-sensitive systems); AI-driven design and optimization of drug delivery systems; sustainability in polymer synthesis, including eco-friendly and bio-based materials
(This special issue belongs to the Section Medicinal Chemistry)
Phytochemistry, Biological Activities and Nanomaterial Applications of Medicinal and Aromatic Plants submission deadline 31 Jan 2027 | Viewed by 260 | Submission Open
Keywords: medicinal and aromatic plants; phytochemicals; bioactive natural products; biological activities; antioxidant and antimicrobial activity; green synthesis of nanoparticles; plant-mediated nanoparticles; metal and metal oxide nanoparticles; nanotechnology in biomedicine
(This special issue belongs to the Section Natural Products Chemistry)
Advances in Phenolic Compounds: Isolation, Characterization, and Bioapplications
edited by Didem Deliorman Orhan and
submission deadline 31 Jan 2027 | Viewed by 259 | Submission Open
Keywords: phenolic compounds; polyphenols; natural products; bioactive compounds; green extraction; functional foods; nutraceuticals
(This special issue belongs to the Section Natural Products Chemistry)
Advanced Research on Computer-Aided Drug Design
edited by , and Özgecan Kayalar
submission deadline 31 Jan 2027 | Viewed by 255 | Submission Open
Keywords: computer-aided drug design; structure-based drug design; molecular docking; molecular dynamics simulations; virtual screening; hit-to-lead optimization; binding free energy; ADMET prediction; machine learning in drug discovery; protein–ligand interactions; mutation-driven drug resistance; computational medicinal chemistry
(This special issue belongs to the Section Medicinal Chemistry)
Design and Functionalization of Semiconductor Nanomaterials for Photocatalysis
edited by Virgínia Ferreira and
submission deadline 31 Jan 2027 | Viewed by 246 | Submission Open
Keywords: photocatalysis; semiconductor nanoparticles; nanomaterials; heterogeneous catalysis; green photo-catalytic reactions; energy conversion; photo-assisted redox processes; pollutants photodegradation
(This special issue belongs to the Section Materials Chemistry)
The Future of Anti-Cancer Agents Driven by High-Throughput Technologies, Computational Chemistry and Artificial Intelligence submission deadline 31 Jan 2027 | Viewed by 241 | Submission Open
Keywords: anti-cancer agents; medicinal chemistry; synthesis and SAR optimization; mechanism of action; oncogenic signaling pathways; chemoresistance; in silico modeling; targeted drug delivery
(This special issue belongs to the Section Medicinal Chemistry)
Current Trends and Challenges in Biosensors for Medical Applications
edited by and Qiming Chen
submission deadline 31 Jan 2027 | Viewed by 241 | Submission Open
Keywords: biosensing chemistry; molecular recognition; analytical chemistry; chemical transduction; functional materials
(This special issue belongs to the Section Applied Chemistry)
Biopolymers for Drug Delivery Systems, 2nd Edition
edited by and Petra Arany
submission deadline 31 Jan 2027 | Viewed by 227 | Submission Open
Keywords: drug delivery systems; biopolymers; personalized medication; nanoparticle; hydrogel; 3D printing
(This special issue belongs to the Section Medicinal Chemistry)
Recent Advances of Nanomaterials in Electrochemistry
edited by Najeeb Lashari
submission deadline 31 Jan 2027 | Viewed by 220 | Submission Open
Keywords: nanomaterials; electrochemistry; nanostructured electrodes; electrocatalysis; energy storage; batteries; supercapacitors; electrochemical sensors; nanocomposites; two-dimensional materials; transition metal oxides; carbon nanomaterials; conductive polymers; interface engineering; charge transport; photoelectrochemistry; green energy technologies; surface chemistry; nano-electrocatalysts; advanced functional materials
(This special issue belongs to the Section Nanochemistry)
Research Progress on Functional Lipids and Their Applications in Health Food Systems—2nd Edition
edited by
submission deadline 31 Jan 2027 | Viewed by 218 | Submission Open
Keywords: lipid crystallization; lipid oxidation; enzymatic lipid modification; processing; health benefits; structured emulsions; lipid emulsions; lipid capsules
(This special issue belongs to the Section Food Chemistry)
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