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Special Issue "Recent Advances in the Superoxide Anion Radical Production and Handling by Biological Systems"

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Bioorganic Chemistry".

Deadline for manuscript submissions: 30 November 2020.

Special Issue Editor

Dr. Alejandro Samhan-Arias
Website SciProfiles
Guest Editor
Departamento de Bioquímica, Universidad Autónoma de Madrid (UAM) e Instituto de Investigaciones Biomédicas ‘Alberto Sols’ (CSIC-UAM). C\ Arturo Duperier, 4 28029 Madrid, Spain
Interests: free radical biology; reactive oxygen species; reactive nitrogen species; peroxidases; NADH oxidases; lipidomics; intrinsically disordered proteins; neurodegenerative diseases; redox biomedicine
Special Issues and Collections in MDPI journals

Special Issue Information

Dear Colleagues,

The reduction of O2 by natural or artificial means transforms molecular O2 into ROS. The superoxide anion radical has attracted the attention of many scientists due to its role in life and disease. The mechanisms of its production and detoxification has been the focus of study for many researchers in the last 50 years. Drs. JoeMcCord and Fridovich discovered the activity of superoxide dismutase early on—a key protein implicated in the detoxification and protection against superoxide anion radical that can be generated by old and recently described mammalian enzymes producing this radical. Moreover, some microorganisms present a different class of enzymes named the superoxide reductases, which are implicated in the detoxification of superoxide anion and protection during infection. This Special Issue is focused on the review of the latest advances in this field.

Prof. Dr. Alejandro K. Samhan-Arias
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • superoxide anion radical
  • superoxide reductases
  • superoxide dismutases
  • antioxidants
  • detection
  • infectivity
  • nitration
  • phosphorylation
  • glutathionylation
  • glycation

Published Papers

This special issue is now open for submission.
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