Special Issue "Silymarin"
Deadline for manuscript submissions: closed (30 November 2016).
Interests: animal experiment; blood–brain barrier; blood–placental barrier; drug–drug interactions; enterohepartic circulation; food chemistry; herbal medicine; liquid chromatography; LC-MS/MS; microdialysis; natural products; neurochemistry; pharmaceutical analysis; pharmacodynamics; pharmacokinetics; traditional Chinese medicine; transportor mechanism
Special Issues and Collections in MDPI journals
In the last decade, the investigation of silymarin has grown to over 100 articles per year. Previous articles revealed that silymarin was a multi-bioactivity component isolated from milk thistle, and its well-known bioactivity has hepatoprotective effects. Recent research has been focused on clinical trials, formulation design, and pharmacokinetic evaluations. Despite its effective bioactivities in vitro, silymarin suffers from poor absorption with low bioavailability, and does not provide an effective efficacy. Because of its significant hepatoprotective, antioxidative, antitumor, and neuroprotective effects, silymarin is frequently co-administered with clinical drugs. Based on the drug safety concern, the herb–drug interaction should be carefully examined. This Special Issue aims to encompass papers at the forefront of research in the field, by dealing with the following topical issues: therapeutic efficacy; efforts to develop new formulations or nano-drug delivery carriers to improve oral bioavailability; prolongation of drug action; herb–drug interaction studies in pre-clinical trials and clinical trials; and the absorption, distribution, metabolism, and elimination studies of silymarin.
As Guest Editors, we cordially invite researchers to submit your work relevant to this Special Issue of Molecules.
Prof. Tung-Hu Tsai
Prof. Youngjin Jeon
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- nature products
- herb-drug interaction
- pharmaceutical formulation