Sample Preparation for Bioanalysis
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Analytical Chemistry".
Deadline for manuscript submissions: closed (28 February 2021) | Viewed by 5477
Special Issue Editor
Interests: separation science (theory and applications in various scientific domains)
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Bioanalysis is a huge domain of research and practice. The analytical interest is prompted by the large variety of biomatrices and, meanwhile, the multitude of analytical techniques and materials utilized for their investigation. Almost all of them require, prior to the analysis, a more or less complex procedure, which is known as sample preparation or sample processing. This is very important for the entire analytical process, because the quality of the analytical data obtained from the analysis is strongly dependent on the choice of the sample preparation procedure. This is why it is said that the sample preparation step can be considered as the “bottleneck” in bioanalysis. Sample preparation has many roles in bioanalysis, such as improving the quality of the analysis or making the sample amenable to the core analytical process. The sample preparation can be innovative, can be a routine procedure, can be applied to a few samples or to large scale studies, can be manual or automated, can be a more or less “green” process, can be tedious or simple, can rely on a chemical and/or physical process, and can vary in many other ways. It is often not a surprise to see publications reporting outstanding methods or materials for sample preparation applied to the new biomatrices. The main directions of this topic could be sample concentration, matrix simplification, chemical modification, automation, optimization, validation and any others that the authors find to be original and worthy of publication. Owing to the large number of achievements reported in the literature, reviews with specific themes will also be highly appreciated. In conclusion, this topical collection attempts to provide a forum for the dissemination of the newest achievements or viewpoints regarding sample preparation for bioanalytical purposes.
Prof. Dr. Victor David
Guest Editor
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Keywords
- Bioanalysis
- Biomatrix
- Extractions
- Derivatization
- Sample clean-up
- Sample enrichment
- Matrix simplification
- Chemometrics
- Optimization
- Validation
- Process modeling
- Electrochemistry
- Spectrometry
- Chromatography
- Automation
- Sources of errors
