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Novel Radiopharmaceuticals for PET and SPECT Imaging

This special issue belongs to the section “Medicinal Chemistry“.

Special Issue Information

Dear Colleagues,

Positron emission tomography (PET) and single-photon emission computed tomography (SPECT) are important imaging techniques in the era of personalized medicine. Both PET and SPECT rely on radiotracers to probe specific biomarkers of disease with exquisite sensitivity, and the resulting images can help guide patient management and improve clinical outcomes. At present, only a very small selection of PET and SPECT radiotracers are used routinely in clinical settings but this is primed for expansion as recent advances in molecular pathology have revealed a wide array of attractive imaging biomarkers for several disease states. This expansion will be facilitated by recent developments in radiochemistry that have provided efficient synthetic routes to hitherto inaccessible radiotracers and also helped foster exciting innovations in probe design. The aim of this Special Issue is to collate examples of novel PET and SPECT radiotracers that have the potential to advance this important medical frontier.

Dr. James C Knight
Guest Editor

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Keywords

  • radiochemistry
  • positron emission tomography
  • single-photon emission computed tomography
  • radiotracers
  • radioligands
  • radiopharmaceuticals
  • molecular imaging
  • early detection
  • monitoring therapy
  • personalized medicine

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Molecules - ISSN 1420-3049