Special Issue "Proteasome Regulators: Activators and Inhibitors"
A special issue of Molecules (ISSN 1420-3049).
Deadline for manuscript submissions: closed (30 June 2019).
Interests: proteasome; heterocycles; drug discovery; chemotherapy; NF-kB; marine sponge metabolites
We are pleased to announce that submissions for the Molecules Special Issue "Proteasome Regulators: Activators and Inhibitors" are now open.
FDA (Food and Drug Administration) approval of the proteasome inhibitors bortezomib and carfilzomib (as well as ixazomib for some patients) as front-line therapy for multiple myeloma and mantle cell lymphoma has validated the proteasome as an important therapeutic target. Following that breakthrough, new research has illuminated other methods of proteasome regulations that have the potential to expand its therapeutic applications.
This Special Issue will focus on new directions in proteasome regulation including proteasome activation and alternative methods of inhibiting its proteolytic activity by small molecules. Original research articles as well as reviews that are able to make substantial advances in this field are welcome.
Dr. Jetze J. Tepe
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.