Porphyrinoid Derivatives: Synthesis and Biological Applications

Dear Colleagues,

Porphyrinoid derivatives are being work-target macrocycles for many research groups; researchers from several areas (mainly from chemistry, physics, biology, pharmacy, and medicine) are looking for new derivatives with potentially significant applications.
The medicinal applications already demonstrated by some porphyrinic formulations in the detection and treatment of cancer (a procedure known as photodynamic therapy, PDT) point to the need of having better, more efficient compounds. Also, another significant application already under study is related to the photodynamic inactivation of microorganisms (PDI), mainly those that are antibiotic resistant.
The physical-chemistry properties of such macrocycles also explain the reason for their interaction with several chemical entities, mainly toxic species. Accordingly, such macrocycles can act as promising sensors (e.g., in water treatments, in food protection, etc).
Then there is a wide range of highly significant applications. This points to the need of having well established synthetic procedures leading to new derivatives, with their properties being well assessed.
Manuscripts describing studies pointing to such targets will be welcome in this Special Issue of Molecules.

Prof. Dr. José A. S. Cavaleiro
Guest Editor

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