Special Issue "Natural Bioactives in Anti-Obesity Therapy"
Deadline for manuscript submissions: closed (31 March 2019).
Obesity is a current global epidemic that has led to a marked increase in metabolic diseases. The risk factors for obesity include genetic and non-genetic factors alike, such as age, physiological condition, dietary behaviors and lifestyle. Since 1980, the number of obese people in the world has doubled. The cause of death from being underweight has shifted to obesity in most countries; moreover, obesity is a major risk factor in some chronic diseases, such as cancer, diabetes, and cardiovascular diseases. Recent studies have highlighted the important role of gut microbiota in obesity and metabolic disorders. Therefore, obesity is a serious health problem. To reduce body weight and adiposity, a change in lifestyle habits is still the crucial cornerstone. Physical activity might be helpful in the prevention of obesity by elevating average daily metabolic rate and increased energy expenditure. Unfortunately, this clinical approach is not long-term lasting and weight regain is often seen. Drugs that prevent weight regain appear necessary in obesity treatment. Although there are many methods and drugs to help people to fight obesity, or to maintain their body weight in order to prevent obesity, each method or drug has their limitations and side effects.
Recently, natural products are popular on the anti-obesity market. More and more research addresses finding natural bioactives from dietary or herbal plants that prevent or control obesity via a chemopreventive strategy. Many dietary bioactives isolated from fruits, vegetables and edible plants, such as anthocyanins from blueberries, epigallocatechin gallate (EGCG) from green tea, nobiletin from citrus peel, and curcumin from turmeric, resveratrol and pterostilbene from berries have been reported for their anti-obesity ability in vivo or in vitro. These natural compounds can decrease fat accumulation through inhibiting adipocyte differentiation, adipogenesis, decreasing triacylglycerol level in high-fat-diet-induced obesity animal models by enhancing lipolysis or reducing lipogenesis pathways.
Research articles or reviews covering all kinds of natural compounds, such as polyphenols, stilbenes, alkaloids, terpenoids, tannins, saponins, glycosides, flavonoids, or derivatives, and their possible mechanisms for reducing fat accumulation or helping to control obesity and obesity related diseases are welcome for inclusion in this Special Issue of Molecules.Prof. Dr. Min-Hsiung Pan
Prof. Dr. Filomena Conforti
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- natural bioactives
- gut microbiota
- energy balance
- high fat diet