Natural Products: Anticancer Potential and Beyond

Dear Colleagues,

In the period of 1981–2010, about 80% of the anticancer drugs approved for clinical use were either natural products or inspired by natural products, highlighting the importance of natural products in cancer treatment. Indeed, many natural products have been introduced into oncological practice and also used as lead compounds for the development of more potent and less toxic anticancer drugs. Many natural product anticancer drugs, including those from plants (e.g., vincristine, paclitaxel, irrinotecan, etoposide, etc.), marine sources (e.g., cytarabine), and microbials (e.g., dactinomycine, doxorubicin, bleomycins, etc.), are currently used in clinics. In this Special Issue, we invite investigators to contribute original research articles, as well as review articles that are related to the application of natural products in the treatment of cancer. We are particularly interested in research that works toward improving the anticancer effects of natural products while reducing their side effects. Potential topics include, but are not limited to:

• The anti-cancer effects of new natural products, and their underlying mechanisms
• Pharmacological interventions for the treatment of cancer in natural products
• The development of new natural products that reverse multi-drug resistance in cancer
• Clinical studies and therapeutic efficacy in anti-cancer natural products.

Prof. Dr. Zhe-Sheng (Jason) Chen
Dr. Dong-Hua Yang
Dr. Mohamed Ali Ibrahim
Collection Editors

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